Employment Changes following Breast Cancer Diagnosis: The Effects of Race and Place

Jennifer C. Spencer, Jason S. Rotter, Jan M. Eberth, Whitney E. Zahnd, Robin C. Vanderpool, Linda K. Ko, Melinda M. Davis, Melissa A. Troester, Andrew F. Olshan, Stephanie B. Wheeler

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The financial implications of breast cancer diagnosis may be greater among rural and black women. Women with incident breast cancer were recruited as part of the Carolina Breast Cancer Study. We compared unadjusted and adjusted prevalence of cancer-related job or income loss, and a composite measure of either outcome, by rural residence and stratified by race. We included 2435 women: 11.7% were rural; 48.5% were black; and 38.0% reported employment changes after diagnosis. Rural women more often reported employment effects, including reduced household income (43.6% vs 35.4%, two-sided ?2 test P =. 04). Rural white, rural black, and urban black women each more often reported income reduction (statistically significant vs. urban white women), although these groups did not meaningfully differ from each other. In multivariable regression, rural differences were mediated by socioeconomic factors, but racial differences remained. Programs and policies to reduce financial toxicity in vulnerable patients should address indirect costs of cancer, including lost wages and employment.

Original languageEnglish (US)
Article numberdjz197
Pages (from-to)647-650
Number of pages4
JournalJournal of the National Cancer Institute
Issue number6
StatePublished - Jun 1 2020
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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