Emerging genomic technology in cancer research: Its application in discovering and developing new therapeutic agents

János L. Tanyi, Wa Cheng Kwai, John P. Lahad, Gordon B. Mills

Research output: Contribution to journalReview articlepeer-review

Abstract

The human genome project has provided a wealth of new information about the sequences of individual genes, their location on chromosomes and abnormalities in human disease, which has the potential to revolutionize progress in advancing medical science. Major technological advances are identifying links between changes in gene and protein expression and cellular function. The resulting alterations in cellular function are directly related to the development and/or progression of human disease. Indeed, the completion of the human genome project combined with rapidly emerging technologies has accelerated the identification of disease associated genetic aberrations and already alters the way in which we manage human disease.

Original languageEnglish (US)
Pages (from-to)62-72
Number of pages11
JournalCME Journal of Gynecologic Oncology
Volume9
Issue number1
StatePublished - Mar 2004
Externally publishedYes

Keywords

  • Cancer
  • Drug development
  • Gene technology
  • Genes
  • Genetic alterations

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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