Emerging genomic technology in cancer research: Its application in discovering and developing new therapeutic agents

János L. Tanyi, Wa Cheng Kwai, John P. Lahad, Gordon B. Mills

    Research output: Contribution to journalReview article

    Abstract

    The human genome project has provided a wealth of new information about the sequences of individual genes, their location on chromosomes and abnormalities in human disease, which has the potential to revolutionize progress in advancing medical science. Major technological advances are identifying links between changes in gene and protein expression and cellular function. The resulting alterations in cellular function are directly related to the development and/or progression of human disease. Indeed, the completion of the human genome project combined with rapidly emerging technologies has accelerated the identification of disease associated genetic aberrations and already alters the way in which we manage human disease.

    Original languageEnglish (US)
    Pages (from-to)62-72
    Number of pages11
    JournalCME Journal of Gynecologic Oncology
    Volume9
    Issue number1
    StatePublished - Mar 1 2004

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    Keywords

    • Cancer
    • Drug development
    • Gene technology
    • Genes
    • Genetic alterations

    ASJC Scopus subject areas

    • Oncology
    • Obstetrics and Gynecology

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