Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy

Morgan Hakki, Janet F. Staab, Kieren A. Marr

Research output: Contribution to journalArticle

127 Scopus citations

Abstract

Clinical failure associated with reduced susceptibility to caspofungin has been described in Candida albicans and C. parapsilosis. We report a case of Candida krusei infection that progressed despite caspofungin therapy. Reduced microbial susceptibility to all three echinocandins (caspofungin, anidulafungin, and micafungin) was noted but was not associated with mutations in FKS1.

Original languageEnglish (US)
Pages (from-to)2522-2524
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume50
Issue number7
DOIs
StatePublished - Jul 2006

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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