Embracing IGRAs in children

Research output: Contribution to journalArticle

Abstract

In children primary tuberculosis disease is more common than reactivation disease. Due to immunologic immaturity, the incidence of TB following infection is higher in young children than in older children and adults. Children are immunologically mature by about 5 years of age, at which time the incidence of TB falls to adult rates and they begin to get adult type disease. When you look at the IGRA studies in children with active TB, and put the studies together, the numbers are still quite small. In seven reported studies looking at the sensitivity of the TST vs. QFT-G/GIT in active TB patients aged

Original languageEnglish (US)
JournalInternational Journal of Tuberculosis and Lung Disease
Volume14
Issue number6 SUPPL. 1
StatePublished - Jun 2010

Fingerprint

Incidence
Tuberculosis
Infection

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

Embracing IGRAs in children. / Lewinsohn, Deborah.

In: International Journal of Tuberculosis and Lung Disease, Vol. 14, No. 6 SUPPL. 1, 06.2010.

Research output: Contribution to journalArticle

@article{50748bd412c04c7faa42dfea3cfdcbf1,
title = "Embracing IGRAs in children",
abstract = "In children primary tuberculosis disease is more common than reactivation disease. Due to immunologic immaturity, the incidence of TB following infection is higher in young children than in older children and adults. Children are immunologically mature by about 5 years of age, at which time the incidence of TB falls to adult rates and they begin to get adult type disease. When you look at the IGRA studies in children with active TB, and put the studies together, the numbers are still quite small. In seven reported studies looking at the sensitivity of the TST vs. QFT-G/GIT in active TB patients aged",
author = "Deborah Lewinsohn",
year = "2010",
month = "6",
language = "English (US)",
volume = "14",
journal = "International Journal of Tuberculosis and Lung Disease",
issn = "1027-3719",
publisher = "International Union against Tubercul. and Lung Dis.",
number = "6 SUPPL. 1",

}

TY - JOUR

T1 - Embracing IGRAs in children

AU - Lewinsohn, Deborah

PY - 2010/6

Y1 - 2010/6

N2 - In children primary tuberculosis disease is more common than reactivation disease. Due to immunologic immaturity, the incidence of TB following infection is higher in young children than in older children and adults. Children are immunologically mature by about 5 years of age, at which time the incidence of TB falls to adult rates and they begin to get adult type disease. When you look at the IGRA studies in children with active TB, and put the studies together, the numbers are still quite small. In seven reported studies looking at the sensitivity of the TST vs. QFT-G/GIT in active TB patients aged

AB - In children primary tuberculosis disease is more common than reactivation disease. Due to immunologic immaturity, the incidence of TB following infection is higher in young children than in older children and adults. Children are immunologically mature by about 5 years of age, at which time the incidence of TB falls to adult rates and they begin to get adult type disease. When you look at the IGRA studies in children with active TB, and put the studies together, the numbers are still quite small. In seven reported studies looking at the sensitivity of the TST vs. QFT-G/GIT in active TB patients aged

UR - http://www.scopus.com/inward/record.url?scp=78649338262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649338262&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:78649338262

VL - 14

JO - International Journal of Tuberculosis and Lung Disease

JF - International Journal of Tuberculosis and Lung Disease

SN - 1027-3719

IS - 6 SUPPL. 1

ER -