Electroshock effects on brain protein synthesis: Relation to brain seizures and retrograde amnesia

Carl W. Cotman, Gary Banker, Steven F. Zornetzer, James L. Mcgaugh

Research output: Contribution to journalArticle

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Abstract

The effects of electroshock on brain seizure activity and brain protein synthesis were studied in male mice. A significant but short-lasting inhibition of brain protein synthesis and an increase in the amount of free leucine were produced by electroshock at intensities above the brain seizure threshold. Electroshock at intensities below the brain seizure threshold did not affect brain protein synthesis.

Original languageEnglish (US)
Pages (from-to)454-456
Number of pages3
JournalScience
Volume173
Issue number3995
DOIs
StatePublished - Jan 1 1971

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