Electrophysiological correlates of cardiac sarcoidosis: An appraisal of current evidence

Mrinal Yadava, Rupa Bala

Research output: Contribution to journalArticle

Abstract

Cardiac sarcoidosis is an underdiagnosed condition that may be present in as many as 25% of patients with systemic sarcoidosis. It is associated with significant morbidity and mortality in affected individuals. The presentation of cardiac involvement in sarcoidosis includes sudden death in the absence of preceding symptoms, conduction disturbances, ventricular arrhythmias, and heart failure. A scarcity of randomized data and a lack of prospective trials underlies the contention between experts on the most appropriate strategies for diagnosis and therapy. This review focuses on the electrophysiological sequelae of the disease, with an emphasis on current diagnostic guidelines, multimodality imaging for early detection, and the role of various therapeutic interventions. Multicentre collaboration is necessary to address the numerous unanswered questions pertaining to management of this disease.

Original languageEnglish (US)
Pages (from-to)392-401
Number of pages10
JournalTurk Kardiyoloji Dernegi Arsivi
Volume43
Issue number4
DOIs
Publication statusPublished - Jun 1 2015

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Keywords

  • Cardiac sarcoidosis
  • Implantable cardioverter-defibrillator
  • Sudden death
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

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