Abstract
A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb355-7 showed a paucity of HLA expression.
Original language | English (US) |
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Pages (from-to) | 690-699 |
Number of pages | 10 |
Journal | Investigative Ophthalmology and Visual Science |
Volume | 28 |
Issue number | 4 |
State | Published - 1987 |
Externally published | Yes |
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience