Elastin as a potential biomaterial

Monica Hinds, Jenny Strooband, Mason Kwong, Dhruv Dayal, Halina BrantZawadzki, Rui Quing Qian, Kenton Gregory

Research output: Contribution to journalArticle

Abstract

Porcine vessels, including aortas and carotids, were digested by boiling them in sodium hydroxide until only elastin remained. Amino acid analysis confirmed the extraction of pure porcine elastin. SEM analysis indicated the fibrous structure. The elastin was characterized with axial and circumferential tensile tests to determine yield strengths, elastic moduli, and expansion ratios. Subdermal implant experiments conducted in BALB/C mice demonstrated both the lack of antigenicity and host response for cross species implantation and the ability to prevent its calcification. Vascular implantations revealed the non-thrombogenic characteristic of elastin.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - 2000

Fingerprint

Elastin
Biomaterials
Boiling liquids
Yield stress
Amino acids
Elastic moduli
Sodium
Scanning electron microscopy
Experiments

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Hinds, M., Strooband, J., Kwong, M., Dayal, D., BrantZawadzki, H., Qian, R. Q., & Gregory, K. (2000). Elastin as a potential biomaterial. Annals of Biomedical Engineering, 28(SUPPL. 1).

Elastin as a potential biomaterial. / Hinds, Monica; Strooband, Jenny; Kwong, Mason; Dayal, Dhruv; BrantZawadzki, Halina; Qian, Rui Quing; Gregory, Kenton.

In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 2000.

Research output: Contribution to journalArticle

Hinds, M, Strooband, J, Kwong, M, Dayal, D, BrantZawadzki, H, Qian, RQ & Gregory, K 2000, 'Elastin as a potential biomaterial', Annals of Biomedical Engineering, vol. 28, no. SUPPL. 1.
Hinds M, Strooband J, Kwong M, Dayal D, BrantZawadzki H, Qian RQ et al. Elastin as a potential biomaterial. Annals of Biomedical Engineering. 2000;28(SUPPL. 1).
Hinds, Monica ; Strooband, Jenny ; Kwong, Mason ; Dayal, Dhruv ; BrantZawadzki, Halina ; Qian, Rui Quing ; Gregory, Kenton. / Elastin as a potential biomaterial. In: Annals of Biomedical Engineering. 2000 ; Vol. 28, No. SUPPL. 1.
@article{deb63af7f46a4028b2d60344cd8f9c0a,
title = "Elastin as a potential biomaterial",
abstract = "Porcine vessels, including aortas and carotids, were digested by boiling them in sodium hydroxide until only elastin remained. Amino acid analysis confirmed the extraction of pure porcine elastin. SEM analysis indicated the fibrous structure. The elastin was characterized with axial and circumferential tensile tests to determine yield strengths, elastic moduli, and expansion ratios. Subdermal implant experiments conducted in BALB/C mice demonstrated both the lack of antigenicity and host response for cross species implantation and the ability to prevent its calcification. Vascular implantations revealed the non-thrombogenic characteristic of elastin.",
author = "Monica Hinds and Jenny Strooband and Mason Kwong and Dhruv Dayal and Halina BrantZawadzki and Qian, {Rui Quing} and Kenton Gregory",
year = "2000",
language = "English (US)",
volume = "28",
journal = "Annals of Biomedical Engineering",
issn = "0090-6964",
publisher = "Springer Netherlands",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Elastin as a potential biomaterial

AU - Hinds, Monica

AU - Strooband, Jenny

AU - Kwong, Mason

AU - Dayal, Dhruv

AU - BrantZawadzki, Halina

AU - Qian, Rui Quing

AU - Gregory, Kenton

PY - 2000

Y1 - 2000

N2 - Porcine vessels, including aortas and carotids, were digested by boiling them in sodium hydroxide until only elastin remained. Amino acid analysis confirmed the extraction of pure porcine elastin. SEM analysis indicated the fibrous structure. The elastin was characterized with axial and circumferential tensile tests to determine yield strengths, elastic moduli, and expansion ratios. Subdermal implant experiments conducted in BALB/C mice demonstrated both the lack of antigenicity and host response for cross species implantation and the ability to prevent its calcification. Vascular implantations revealed the non-thrombogenic characteristic of elastin.

AB - Porcine vessels, including aortas and carotids, were digested by boiling them in sodium hydroxide until only elastin remained. Amino acid analysis confirmed the extraction of pure porcine elastin. SEM analysis indicated the fibrous structure. The elastin was characterized with axial and circumferential tensile tests to determine yield strengths, elastic moduli, and expansion ratios. Subdermal implant experiments conducted in BALB/C mice demonstrated both the lack of antigenicity and host response for cross species implantation and the ability to prevent its calcification. Vascular implantations revealed the non-thrombogenic characteristic of elastin.

UR - http://www.scopus.com/inward/record.url?scp=0034499652&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034499652&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034499652

VL - 28

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

SN - 0090-6964

IS - SUPPL. 1

ER -