Efforts to enhance catheter stability improve atrial fibrillation ablation outcome

Mathew D. Hutchinson, Fermin C. Garcia, Jeff E. Mandel, Nabil Elkassabany, Erica S. Zado, Michael P. Riley, Joshua M. Cooper, Rupa Bala, David S. Frankel, David Lin, Gregory E. Supple, Sanjay Dixit, Edward P. Gerstenfeld, David J. Callans, Francis E. Marchlinski

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Background: Contemporary techniques to enhance anatomical detail and catheter contact during atrial fibrillation (AF) ablation include (1) the integration of preacquired tomographic reconstructions with electroanatomical mapping (3-dimensional image integration [I-EAM]), (2) the use of steerable introducers (SIs), and (3) high-frequency jet ventilation (HFJV). Objective: To prove that using these stabilizing techniques during AF ablation improves 1-year procedural outcome. Methods: We studied 300 patients undergoing AF ablation at our institution. Patients were divided into 3 equal treatment groups (100 patients each) on the basis of the tools utilized: (1) group 1: AF ablation performed without I-EAM, SI, or HFJV; (2) group 2: AF ablation performed using I-EAM and SI, but without HFJV; and (3) group 3: AF ablation performed with I-EAM, SI, and HFJV. The primary outcome was freedom from AF 1 year after a single ablation procedure. The burden of both acute and chronic pulmonary vein reconnection was also assessed. Results: Patients from groups 2 and 3 had significantly more nonparoxysmal AF (17% vs 30% vs 39%; P =.002), larger left atria (4.2±0.8 cm vs 4.4±0.7 cm vs 4.5±0.8 cm; P<.001), and higher body mass index (BMI; 28.5±5.8 kg/m2 vs 29.1±4.8 kg/m2 vs 31.2±5.4 kg/m2; P<.001). Despite these differences, with adoption of I-EAM, SI, and HFJV we noted a significant improvement in 1-year freedom from AF (52% vs 66% vs 74%; P =.006) as well as fewer acute (1.1±1.2 vs 0.9±1.1 vs 0.6±0.9; P =.03) and chronic (3.5±0.9 vs 3.2±0.9 vs 2.4±1.0; P =.02) pulmonary vein reconnections. Conclusions: The incorporation of contemporary tools to enhance anatomical detail and ablation catheter stability significantly improved 1-year freedom from AF after ablation.

Original languageEnglish (US)
Pages (from-to)347-353
Number of pages7
JournalHeart Rhythm
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2013

Keywords

  • Atrial fibrillation
  • Catheter ablation
  • High-frequency jet ventilation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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