Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa

Kinnor Das, Steven Daveluy, George Kroumpouzos, Komal Agarwal, Indrashis Podder, Katherine Farnbach, Alex G. Ortega-Loayza, Jacek C. Szepietowski, Stephan Grabbe, Mohamad Goldust

Research output: Contribution to journalReview articlepeer-review

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.

Original languageEnglish (US)
Article number670
JournalJournal of Clinical Medicine
Volume11
Issue number3
DOIs
StatePublished - Feb 1 2022

Keywords

  • Hidradenitis suppurativa
  • Immunosuppressants
  • Treatment

ASJC Scopus subject areas

  • Medicine(all)

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