Effects of the novel cannabinoid CB1 receptor antagonist PF 514273 on the acquisition and expression of ethanol conditioned place preference

Medicine & Life Sciences

• 2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo(3,4-f)(1,4)oxazepin-8(5H)-one 100%
• Cannabinoid Receptor Antagonists 58%
• Ethanol 34%
• Cannabinoid Receptor CB1 19%
• Reward 17%
• Oral Administration 6%
• Consummatory Behavior 6%
• Eating 5%
• Appetite Depressants 4%
• Inbred DBA Mouse 4%
• Locomotion 3%
• Alcoholism 3%
• Animal Models 2%
• Obesity 2%
• Pharmaceutical Preparations 1%
• Therapeutics 1%

Chemical Compounds

• Cannabinoid 1 Receptor Antagonist 71%
• Ethanol 26%
• Antagonist 10%
• Anorectic 9%
• Route of Application 8%
• Cannabinoid 7%
• Dose 4%
• Drug 3%

Social Sciences

• reward 35%
• antagonism 29%
• paradigm 10%
• conditioning 8%
• alcoholism 8%
• liability 7%
• animal 6%
• drug 5%