Effects of smoking and smoking cessation on longitudinal decline in pulmonary function

C. M. Burchfiel, E. B. Marcus, J. D. Curb, C. J. MacLean, W. M. Vollmer, L. R. Johnson, K. O. Fong, B. L. Rodriguez, K. H. Masaki, A (Sonia) Buist

Research output: Contribution to journalArticle

139 Citations (Scopus)

Abstract

Effects of cigarette smoking and smoking cessation on rate of FEV1 decline over 6 yr were examined in 4,451 Japanese-American men from the Honolulu Heart Program who were 45 to 68 yr of age at baseline (1965-1968). Within-person regression was used to calculate annual change in FEV1. Rates of FEV1 decline varied strongly with smoking status and increased significantly with age. Overall, men who continued to smoke experienced steeper rates of decline compared with men who never smoked (-33 ml/yr versus -22 ml/yr, respectively; p = 0.0001). Rates of decline for those who quit smoking during the first 2 yr (-32 ml/yr) were nearly the same as those who continued smoking (-34 ml/yr). After quitting, their rates of decline diminished to a level (-19 ml/yr) similar to that of men who had never smoked (-21 ml/yr). FEV1 decline in continuing smokers was significantly associated with duration of smoking, whereas associations with intensity and pack-years were of borderline significance. Among 216 men with impaired pulmonary function, those who quit smoking had significantly slower rates of FEV1 decline than did those who continued smoking. Potential reasons for quitting included respiratory conditions and stroke. These results extend previous reports of accelerated rates of FEV1 decline in the persons who continue to smoke, and they indicates that smoking cessation leads to less steep rates of decline in pulmonary function over a short period of time in middle-aged men, as well as in men with established pulmonary impairment.

Original languageEnglish (US)
Pages (from-to)1778-1785
Number of pages8
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume151
Issue number6
StatePublished - 1995
Externally publishedYes

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Smoking Cessation
Smoking
Lung
Smoke
Asian Americans
Stroke

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Burchfiel, C. M., Marcus, E. B., Curb, J. D., MacLean, C. J., Vollmer, W. M., Johnson, L. R., ... Buist, A. S. (1995). Effects of smoking and smoking cessation on longitudinal decline in pulmonary function. American Journal of Respiratory and Critical Care Medicine, 151(6), 1778-1785.

Effects of smoking and smoking cessation on longitudinal decline in pulmonary function. / Burchfiel, C. M.; Marcus, E. B.; Curb, J. D.; MacLean, C. J.; Vollmer, W. M.; Johnson, L. R.; Fong, K. O.; Rodriguez, B. L.; Masaki, K. H.; Buist, A (Sonia).

In: American Journal of Respiratory and Critical Care Medicine, Vol. 151, No. 6, 1995, p. 1778-1785.

Research output: Contribution to journalArticle

Burchfiel, CM, Marcus, EB, Curb, JD, MacLean, CJ, Vollmer, WM, Johnson, LR, Fong, KO, Rodriguez, BL, Masaki, KH & Buist, AS 1995, 'Effects of smoking and smoking cessation on longitudinal decline in pulmonary function', American Journal of Respiratory and Critical Care Medicine, vol. 151, no. 6, pp. 1778-1785.
Burchfiel CM, Marcus EB, Curb JD, MacLean CJ, Vollmer WM, Johnson LR et al. Effects of smoking and smoking cessation on longitudinal decline in pulmonary function. American Journal of Respiratory and Critical Care Medicine. 1995;151(6):1778-1785.
Burchfiel, C. M. ; Marcus, E. B. ; Curb, J. D. ; MacLean, C. J. ; Vollmer, W. M. ; Johnson, L. R. ; Fong, K. O. ; Rodriguez, B. L. ; Masaki, K. H. ; Buist, A (Sonia). / Effects of smoking and smoking cessation on longitudinal decline in pulmonary function. In: American Journal of Respiratory and Critical Care Medicine. 1995 ; Vol. 151, No. 6. pp. 1778-1785.
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