Effects of prenalterol on renal function in normal man

Per-Olof Järnberg, L. Westman

Research output: Contribution to journalArticle

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Abstract

The effects of prenalterol infusion, 0.5 μg/kg/min, on renal function were studied in 10 male volunteers. Systolic blood pressure increased by 22 mmHg (P <0.01) and diastolic pressure decreased by 11 mmHg (P <0.01). Heart rate increased by 11 beats/min (P <0.01). Plasma catecholamine levels and plasma renin activity were not altered. Renal haemodynamics were unchanged. Urine flow rate and fractional free water excretion decreased by 29% and 45%, respectively (P <0.01). Fractional sodium excretion increased by 19% (P <0.01) and fractional potassium excretion fell by 33% (P <0.05).

Original languageEnglish (US)
Pages (from-to)603-606
Number of pages4
JournalActa Anaesthesiologica Scandinavica
Volume26
Issue number6
Publication statusPublished - 1982
Externally publishedYes

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ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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