The effects of prenalterol infusion, 0.5 μg/kg/min, on renal function were studied in 10 male volunteers. Systolic blood pressure increased by 22 mmHg (P <0.01) and diastolic pressure decreased by 11 mmHg (P <0.01). Heart rate increased by 11 beats/min (P <0.01). Plasma catecholamine levels and plasma renin activity were not altered. Renal haemodynamics were unchanged. Urine flow rate and fractional free water excretion decreased by 29% and 45%, respectively (P <0.01). Fractional sodium excretion increased by 19% (P <0.01) and fractional potassium excretion fell by 33% (P <0.05).
|Original language||English (US)|
|Number of pages||4|
|Journal||Acta Anaesthesiologica Scandinavica|
|Publication status||Published - 1982|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine