Effects of positive end-expiratory pressure on renal function

Per-Olof Järnberg, E. Dominguez De Villota, J. Eklund, P. O. Granberg

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The effects were studied of positive end-expiratory pressure (PEEP) on renal function in eight patients with acute respiratory failure, requiring mechanical ventilation. On application of PEEP+10 cmH2O, central venous pressure increased, systolic blood pressure decreased, uring flow and PAH-clearance were reduced, while insulin clearance remained stable. There was a marked increase in fractional sodium reabsorption and a concurrent decrease in fractional osmolal excretion. Fractional free-water clearance and the ratio U(osm)/P(osm) did not change.

Original languageEnglish (US)
Pages (from-to)508-514
Number of pages7
JournalActa Anaesthesiologica Scandinavica
Volume22
Issue number5
StatePublished - 1978
Externally publishedYes

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Positive-Pressure Respiration
Blood Pressure
Kidney
Central Venous Pressure
Artificial Respiration
Respiratory Insufficiency
Sodium
Insulin
Water

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Järnberg, P-O., Dominguez De Villota, E., Eklund, J., & Granberg, P. O. (1978). Effects of positive end-expiratory pressure on renal function. Acta Anaesthesiologica Scandinavica, 22(5), 508-514.

Effects of positive end-expiratory pressure on renal function. / Järnberg, Per-Olof; Dominguez De Villota, E.; Eklund, J.; Granberg, P. O.

In: Acta Anaesthesiologica Scandinavica, Vol. 22, No. 5, 1978, p. 508-514.

Research output: Contribution to journalArticle

Järnberg, P-O, Dominguez De Villota, E, Eklund, J & Granberg, PO 1978, 'Effects of positive end-expiratory pressure on renal function', Acta Anaesthesiologica Scandinavica, vol. 22, no. 5, pp. 508-514.
Järnberg P-O, Dominguez De Villota E, Eklund J, Granberg PO. Effects of positive end-expiratory pressure on renal function. Acta Anaesthesiologica Scandinavica. 1978;22(5):508-514.
Järnberg, Per-Olof ; Dominguez De Villota, E. ; Eklund, J. ; Granberg, P. O. / Effects of positive end-expiratory pressure on renal function. In: Acta Anaesthesiologica Scandinavica. 1978 ; Vol. 22, No. 5. pp. 508-514.
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