TY - JOUR
T1 - Effects of Positive End‐Expiratory Pressure on Renal Function
AU - Järnberg, P. ‐O
AU - de Villota, E. Dominguez
AU - Eklund, J.
AU - Granberg, P. ‐O
PY - 1978/10
Y1 - 1978/10
N2 - The effects were studied of positive end‐expiratory pressure (PEEP) on renal function in eight patients with acute respiratory failure, requiring mechanical ventilation. On application of PEEP+ 10 cmH2O, central venous pressure increased, systolic blood pressure decreased, urine flow and PAH‐clearance were reduced, while inulin clearance remained stable. There was a marked increase in fractional sodium reabsorption and a concurrent decrease in fractional osmolal excretion. Fractional free‐water clearance and the ratio Uosm/Posm did not change.
AB - The effects were studied of positive end‐expiratory pressure (PEEP) on renal function in eight patients with acute respiratory failure, requiring mechanical ventilation. On application of PEEP+ 10 cmH2O, central venous pressure increased, systolic blood pressure decreased, urine flow and PAH‐clearance were reduced, while inulin clearance remained stable. There was a marked increase in fractional sodium reabsorption and a concurrent decrease in fractional osmolal excretion. Fractional free‐water clearance and the ratio Uosm/Posm did not change.
UR - http://www.scopus.com/inward/record.url?scp=0017851774&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017851774&partnerID=8YFLogxK
U2 - 10.1111/j.1399-6576.1978.tb01331.x
DO - 10.1111/j.1399-6576.1978.tb01331.x
M3 - Article
C2 - 358723
AN - SCOPUS:0017851774
SN - 0001-5172
VL - 22
SP - 508
EP - 514
JO - Acta Anaesthesiologica Scandinavica
JF - Acta Anaesthesiologica Scandinavica
IS - 5
ER -