TY - JOUR
T1 - Effects of methotrexate on transfected DNA stability in mammalian cells
AU - Pallavicini, Maria G.
AU - Deteresa, Patricia S.
AU - Rosette, Caridad
AU - Gray, Joe W.
AU - Wurm, Florian M.
PY - 1990/1
Y1 - 1990/1
N2 - The chromosomal locations, amounts, and level of expression of transfected, amplified c-myc and dihydrofolate reductase sequences were measured in cells cultured in the presence and absence of methotrexate. These studies show that the location and amount of transfected sequences, as well as the level of expression, were more variable when the cells were cultured in methotrexate.
AB - The chromosomal locations, amounts, and level of expression of transfected, amplified c-myc and dihydrofolate reductase sequences were measured in cells cultured in the presence and absence of methotrexate. These studies show that the location and amount of transfected sequences, as well as the level of expression, were more variable when the cells were cultured in methotrexate.
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U2 - 10.1128/MCB.10.1.401
DO - 10.1128/MCB.10.1.401
M3 - Article
C2 - 2403643
AN - SCOPUS:0025139423
SN - 0270-7306
VL - 10
SP - 401
EP - 404
JO - Molecular and cellular biology
JF - Molecular and cellular biology
IS - 1
ER -