Effects of late (1 to 30 days) reperfusion after acute myocardial infarction on the signal-averaged electrocardiogram

Michael Ragosta, Peter J. Sabia, Sanjiv Kaul, John P. DiMarco, Ian J. Sarembock, Eric R. Powers

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Early reperfusion (4 to 6 hours) after acute myocardial infarction reduces mortality and reduces the incidence of late potentials on a signal-averaged electrocardiogram (SAECG). Recent reports suggest that reperfusion accomplished after >6 hours also may reduce mortality. The effect of such later reperfusion on the SAECG is not known. We hypothesized that reperfusion by angioplasty accomplished >24 hours after onset of infarction would reduce late potentials and improve the parameters on the SAECG. Forty-one patients with a totally occluded infarct-related artery 12 ± 8 days after infarction underwent attempted angioplasty. SAECG, echocardiography and thallium-201 imaging were performed before and 1 month after attempted angioplasty. Angioplasty resulted in successful reperfusion in 32 patients and was unsuccessful in 9. No change in the incidence of late potentials occurred after successful reperfusion (13 of 32 patients before and 13 of 32 patients 1 month later) or after unsuccessful reperfusion (6 of 9 patients before and 5 of 9 patients 1 month later). Among patients with successful reperfusion, no significant change occurred in the QRS duration or the terminal signal duration

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalThe American Journal of Cardiology
Volume71
Issue number1
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

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Reperfusion
Electrocardiography
Myocardial Infarction
Angioplasty
Infarction
Mortality
Thallium
Incidence
Echocardiography
Arteries

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Effects of late (1 to 30 days) reperfusion after acute myocardial infarction on the signal-averaged electrocardiogram. / Ragosta, Michael; Sabia, Peter J.; Kaul, Sanjiv; DiMarco, John P.; Sarembock, Ian J.; Powers, Eric R.

In: The American Journal of Cardiology, Vol. 71, No. 1, 01.01.1993, p. 19-23.

Research output: Contribution to journalArticle

Ragosta, Michael ; Sabia, Peter J. ; Kaul, Sanjiv ; DiMarco, John P. ; Sarembock, Ian J. ; Powers, Eric R. / Effects of late (1 to 30 days) reperfusion after acute myocardial infarction on the signal-averaged electrocardiogram. In: The American Journal of Cardiology. 1993 ; Vol. 71, No. 1. pp. 19-23.
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