Effects of grwoth hormone therapy and malnutrition on the growth of rats with renal failure

David R. Powell, Ronald (Ron) Rosenfeld, Raymond L. Hintz

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

We examined the effects of methionylhuman growth hormone (met-hGH) and malnutrition on the growth of 5/6 nephrectomized rats and sham-operated controls. One group of shamoperated rats (PFS) was pair-fed with a group of nephrectomized rats in renal failure (RF); another group of sham-operated rats was fed ad libitum (ALS), and a final group of rats with renal failure (RF-GH) was treated with 4 IU/day met-hGH. After 4 weeks, RF-GH rats gained 12.3±1.7 cm in length; this was more than the 10.2±1.2 cm gain of RF rats (PPFS>RF, P

Original languageEnglish (US)
Pages (from-to)425-430
Number of pages6
JournalPediatric Nephrology
Volume2
Issue number4
DOIs
StatePublished - Dec 1988
Externally publishedYes

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Malnutrition
Renal Insufficiency
Hormones
Growth
Therapeutics
Growth Hormone

Keywords

  • Growth
  • Growth hormone therapy
  • Malnutrition
  • Renal failure

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

Cite this

Effects of grwoth hormone therapy and malnutrition on the growth of rats with renal failure. / Powell, David R.; Rosenfeld, Ronald (Ron); Hintz, Raymond L.

In: Pediatric Nephrology, Vol. 2, No. 4, 12.1988, p. 425-430.

Research output: Contribution to journalArticle

Powell, David R. ; Rosenfeld, Ronald (Ron) ; Hintz, Raymond L. / Effects of grwoth hormone therapy and malnutrition on the growth of rats with renal failure. In: Pediatric Nephrology. 1988 ; Vol. 2, No. 4. pp. 425-430.
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