Effects of adjacent surfaces of different shapes on regurgitant jet sizes: An in vitro study using color Doppler imaging and laser-illuminated dye visualization

Jun Zhang, Takahiro Shiota, Robin Shandas, You Bin Deng, Robert Weintraub, Juliana Paik, Dorian Liepmann, David Sahn

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objetives. The present study was designed to estimate the influence of different-shaped adjacent surfaces on regurgitant jets as assessed by color Doppler imaging and laser-Illuminated dye optical visualisation,. Background. Because color Doppler techniques provide real-time two-dimentional imaging of flow, the evaluation of valvular regurgitation by analysis of variance-encoded regurgitant jets by this method has been widely used in clinical studies. However, recent studies have demonstrated that color Doppler jet sizes are affected not only by several hemodynamk factors and instrument settings but also by the interaction between jets and adjacent wall surfaces. In clinical conditions, jets may interact with adjacent walls of variable shapes that might have different effects on the jet size. Methods. An in vitro model was constructed consisting of a rigid, optically clear receiving chamber that had no outlet resistance and had a pulsatile pump ejecting through 1.5, 2.3 and 3.1 mm2 inflow orifices into the chamber. The surfaces were flat or smoothly and equally curved, convex and concave aluminum positioned at 0,2 and 4 mm from and to the side of the inflow orifices. The pump was run with stroke volumes from 0.5 to 3.0 ml and with a pulse frequency of 70 beats/min, The echocardiographic and laser beams were aimed at the inflow orifice imaging jets perpendicular to the surfaces (vertical view) through the central plane of the jet flows. Maximal jet areas were measured by both color Doppler techniques and laser-illuminated dye visualization. Results. Color Doppler study showed fair correlation between the jet areas and the stroke volumes (r = 0.83 to 0.99), but the jet sizes under different surface conditions were variable. All the surface jet areas at a jet-surface distance of 0 and 2 mm were smaller than free jet areas at the same stroke volume for both flat and convex surfaces (p <0.001). Flow constraint by the concave surface resulted in the smallest jet areas (p <0.001). The color Doppler jet areas on the curved surfaces were significantly smaller than the laser-illuminated dye visualization jet areas (p <0.01 to 0.0001). However, at intermediate jet-surface distances (4 mm and sometimes 2 mm with higher velocity flows), jet interaction with the flat and especially with the convex surface resulted in larger jets. This effect was most pronounced on dye fluorescence studies because flow around these jets consisted mainly of low velocity vortical events with only partial surface adherence and these low velocity swirling flows were not well imaged by color Doppler technique. Conclusions. Our study suggests that the different-shaped adjacent surfaces with different degrees of flow alterations resulted in variable decreases in jet size and that color Doppler imaging could not encode and image the angled and low velocity swirling events well when jets flowed along the curved surfaces. These effects need to be taken into account when interpreting color Doppler images.

Original languageEnglish (US)
Pages (from-to)1522-1529
Number of pages8
JournalJournal of the American College of Cardiology
Volume22
Issue number5
DOIs
StatePublished - Nov 1 1993
Externally publishedYes

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Dye Lasers
Color
Stroke Volume
In Vitro Techniques
Aluminum
Pulse
Analysis of Variance
Lasers
Coloring Agents
Fluorescence

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Effects of adjacent surfaces of different shapes on regurgitant jet sizes : An in vitro study using color Doppler imaging and laser-illuminated dye visualization. / Zhang, Jun; Shiota, Takahiro; Shandas, Robin; Deng, You Bin; Weintraub, Robert; Paik, Juliana; Liepmann, Dorian; Sahn, David.

In: Journal of the American College of Cardiology, Vol. 22, No. 5, 01.11.1993, p. 1522-1529.

Research output: Contribution to journalArticle

Zhang, Jun ; Shiota, Takahiro ; Shandas, Robin ; Deng, You Bin ; Weintraub, Robert ; Paik, Juliana ; Liepmann, Dorian ; Sahn, David. / Effects of adjacent surfaces of different shapes on regurgitant jet sizes : An in vitro study using color Doppler imaging and laser-illuminated dye visualization. In: Journal of the American College of Cardiology. 1993 ; Vol. 22, No. 5. pp. 1522-1529.
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title = "Effects of adjacent surfaces of different shapes on regurgitant jet sizes: An in vitro study using color Doppler imaging and laser-illuminated dye visualization",
abstract = "Objetives. The present study was designed to estimate the influence of different-shaped adjacent surfaces on regurgitant jets as assessed by color Doppler imaging and laser-Illuminated dye optical visualisation,. Background. Because color Doppler techniques provide real-time two-dimentional imaging of flow, the evaluation of valvular regurgitation by analysis of variance-encoded regurgitant jets by this method has been widely used in clinical studies. However, recent studies have demonstrated that color Doppler jet sizes are affected not only by several hemodynamk factors and instrument settings but also by the interaction between jets and adjacent wall surfaces. In clinical conditions, jets may interact with adjacent walls of variable shapes that might have different effects on the jet size. Methods. An in vitro model was constructed consisting of a rigid, optically clear receiving chamber that had no outlet resistance and had a pulsatile pump ejecting through 1.5, 2.3 and 3.1 mm2 inflow orifices into the chamber. The surfaces were flat or smoothly and equally curved, convex and concave aluminum positioned at 0,2 and 4 mm from and to the side of the inflow orifices. The pump was run with stroke volumes from 0.5 to 3.0 ml and with a pulse frequency of 70 beats/min, The echocardiographic and laser beams were aimed at the inflow orifice imaging jets perpendicular to the surfaces (vertical view) through the central plane of the jet flows. Maximal jet areas were measured by both color Doppler techniques and laser-illuminated dye visualization. Results. Color Doppler study showed fair correlation between the jet areas and the stroke volumes (r = 0.83 to 0.99), but the jet sizes under different surface conditions were variable. All the surface jet areas at a jet-surface distance of 0 and 2 mm were smaller than free jet areas at the same stroke volume for both flat and convex surfaces (p <0.001). Flow constraint by the concave surface resulted in the smallest jet areas (p <0.001). The color Doppler jet areas on the curved surfaces were significantly smaller than the laser-illuminated dye visualization jet areas (p <0.01 to 0.0001). However, at intermediate jet-surface distances (4 mm and sometimes 2 mm with higher velocity flows), jet interaction with the flat and especially with the convex surface resulted in larger jets. This effect was most pronounced on dye fluorescence studies because flow around these jets consisted mainly of low velocity vortical events with only partial surface adherence and these low velocity swirling flows were not well imaged by color Doppler technique. Conclusions. Our study suggests that the different-shaped adjacent surfaces with different degrees of flow alterations resulted in variable decreases in jet size and that color Doppler imaging could not encode and image the angled and low velocity swirling events well when jets flowed along the curved surfaces. These effects need to be taken into account when interpreting color Doppler images.",
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T2 - An in vitro study using color Doppler imaging and laser-illuminated dye visualization

AU - Zhang, Jun

AU - Shiota, Takahiro

AU - Shandas, Robin

AU - Deng, You Bin

AU - Weintraub, Robert

AU - Paik, Juliana

AU - Liepmann, Dorian

AU - Sahn, David

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N2 - Objetives. The present study was designed to estimate the influence of different-shaped adjacent surfaces on regurgitant jets as assessed by color Doppler imaging and laser-Illuminated dye optical visualisation,. Background. Because color Doppler techniques provide real-time two-dimentional imaging of flow, the evaluation of valvular regurgitation by analysis of variance-encoded regurgitant jets by this method has been widely used in clinical studies. However, recent studies have demonstrated that color Doppler jet sizes are affected not only by several hemodynamk factors and instrument settings but also by the interaction between jets and adjacent wall surfaces. In clinical conditions, jets may interact with adjacent walls of variable shapes that might have different effects on the jet size. Methods. An in vitro model was constructed consisting of a rigid, optically clear receiving chamber that had no outlet resistance and had a pulsatile pump ejecting through 1.5, 2.3 and 3.1 mm2 inflow orifices into the chamber. The surfaces were flat or smoothly and equally curved, convex and concave aluminum positioned at 0,2 and 4 mm from and to the side of the inflow orifices. The pump was run with stroke volumes from 0.5 to 3.0 ml and with a pulse frequency of 70 beats/min, The echocardiographic and laser beams were aimed at the inflow orifice imaging jets perpendicular to the surfaces (vertical view) through the central plane of the jet flows. Maximal jet areas were measured by both color Doppler techniques and laser-illuminated dye visualization. Results. Color Doppler study showed fair correlation between the jet areas and the stroke volumes (r = 0.83 to 0.99), but the jet sizes under different surface conditions were variable. All the surface jet areas at a jet-surface distance of 0 and 2 mm were smaller than free jet areas at the same stroke volume for both flat and convex surfaces (p <0.001). Flow constraint by the concave surface resulted in the smallest jet areas (p <0.001). The color Doppler jet areas on the curved surfaces were significantly smaller than the laser-illuminated dye visualization jet areas (p <0.01 to 0.0001). However, at intermediate jet-surface distances (4 mm and sometimes 2 mm with higher velocity flows), jet interaction with the flat and especially with the convex surface resulted in larger jets. This effect was most pronounced on dye fluorescence studies because flow around these jets consisted mainly of low velocity vortical events with only partial surface adherence and these low velocity swirling flows were not well imaged by color Doppler technique. Conclusions. Our study suggests that the different-shaped adjacent surfaces with different degrees of flow alterations resulted in variable decreases in jet size and that color Doppler imaging could not encode and image the angled and low velocity swirling events well when jets flowed along the curved surfaces. These effects need to be taken into account when interpreting color Doppler images.

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