Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels

Annabel Chen-Tournoux, Abigail Khan, Aaron L. Baggish, Victor M. Castro, Marc J. Semigran, Elizabeth L. McCabe, George Moukarbel, Jason Reingold, Sofia Durrani, Gregory D. Lewis, Christopher Newton-Cheh, Marielle Scherrer-Crosbie, Lee M. Kaplan, Thomas J. Wang

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Natriuretic peptides have multiple beneficial cardiovascular effects. Previous cross-sectional studies have indicated that obese subjects have lower natriuretic peptide concentrations than those of normal weight. It is not known whether this relative natriuretic peptide deficiency is reversible with weight loss. We studied 132 obese subjects undergoing weight loss surgery with serial measurement of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations at preoperative, early (1 to 2 months), and late postoperative (6 months) points. In addition, 20 subjects also underwent echocardiography at baseline and 6 months after surgery. Significant weight loss was observed after surgery (median body mass index 45.1, 41.0, and 32.9 kg/m2 for the 3 corresponding points, analysis of variance p

Original languageEnglish (US)
Pages (from-to)1450-1455
Number of pages6
JournalAmerican Journal of Cardiology
Volume106
Issue number10
DOIs
StatePublished - Nov 15 2010
Externally publishedYes

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Natriuretic Peptides
Brain Natriuretic Peptide
Weight Loss
Echocardiography
Analysis of Variance
Body Mass Index
Cross-Sectional Studies
Weights and Measures

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chen-Tournoux, A., Khan, A., Baggish, A. L., Castro, V. M., Semigran, M. J., McCabe, E. L., ... Wang, T. J. (2010). Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels. American Journal of Cardiology, 106(10), 1450-1455. https://doi.org/10.1016/j.amjcard.2010.06.076

Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels. / Chen-Tournoux, Annabel; Khan, Abigail; Baggish, Aaron L.; Castro, Victor M.; Semigran, Marc J.; McCabe, Elizabeth L.; Moukarbel, George; Reingold, Jason; Durrani, Sofia; Lewis, Gregory D.; Newton-Cheh, Christopher; Scherrer-Crosbie, Marielle; Kaplan, Lee M.; Wang, Thomas J.

In: American Journal of Cardiology, Vol. 106, No. 10, 15.11.2010, p. 1450-1455.

Research output: Contribution to journalArticle

Chen-Tournoux, A, Khan, A, Baggish, AL, Castro, VM, Semigran, MJ, McCabe, EL, Moukarbel, G, Reingold, J, Durrani, S, Lewis, GD, Newton-Cheh, C, Scherrer-Crosbie, M, Kaplan, LM & Wang, TJ 2010, 'Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels', American Journal of Cardiology, vol. 106, no. 10, pp. 1450-1455. https://doi.org/10.1016/j.amjcard.2010.06.076
Chen-Tournoux, Annabel ; Khan, Abigail ; Baggish, Aaron L. ; Castro, Victor M. ; Semigran, Marc J. ; McCabe, Elizabeth L. ; Moukarbel, George ; Reingold, Jason ; Durrani, Sofia ; Lewis, Gregory D. ; Newton-Cheh, Christopher ; Scherrer-Crosbie, Marielle ; Kaplan, Lee M. ; Wang, Thomas J. / Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels. In: American Journal of Cardiology. 2010 ; Vol. 106, No. 10. pp. 1450-1455.
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