Effect of variable doses of dexamethasone on posttreatment endodontic pain

Alan Liesinger, F. James Marshall, J (Gordon) Marshall

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

One hundred six patients with pretreatment pain presenting for endodontic treatment participated in a controlled double blind study. After root canal therapy, the patients were given an intraoral intramuscular injection of either a saline placebo or various dosages of dexamethasone. Posttreatment pain incidence and severity were evaluated at 4, 8, 24, 48, and 72 h. Injection of the various dosages of dexamethasone, taken as a group, was shown to significantly reduce the severity of pain at 4 and 8 h, and 0.07 to 0.09 mg/kg dosage alone significantly reduced pain at 8 h. Patients who received dexamethasone took significantly fewer posttreatment pain medications than those who received the placebo. Although there was a trend toward a reduction in the incidence of posttreatment pain for patients who received dexamethasone, the difference was not statistically significant.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
JournalJournal of Endodontics
Volume19
Issue number1
DOIs
StatePublished - 1993
Externally publishedYes

Fingerprint

Endodontics
Dexamethasone
Pain
Placebos
Root Canal Therapy
Intramuscular Injections
Incidence
Double-Blind Method
Injections

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Effect of variable doses of dexamethasone on posttreatment endodontic pain. / Liesinger, Alan; Marshall, F. James; Marshall, J (Gordon).

In: Journal of Endodontics, Vol. 19, No. 1, 1993, p. 35-39.

Research output: Contribution to journalArticle

Liesinger, Alan ; Marshall, F. James ; Marshall, J (Gordon). / Effect of variable doses of dexamethasone on posttreatment endodontic pain. In: Journal of Endodontics. 1993 ; Vol. 19, No. 1. pp. 35-39.
@article{61612219e00b4e36b683fc594b886dc0,
title = "Effect of variable doses of dexamethasone on posttreatment endodontic pain",
abstract = "One hundred six patients with pretreatment pain presenting for endodontic treatment participated in a controlled double blind study. After root canal therapy, the patients were given an intraoral intramuscular injection of either a saline placebo or various dosages of dexamethasone. Posttreatment pain incidence and severity were evaluated at 4, 8, 24, 48, and 72 h. Injection of the various dosages of dexamethasone, taken as a group, was shown to significantly reduce the severity of pain at 4 and 8 h, and 0.07 to 0.09 mg/kg dosage alone significantly reduced pain at 8 h. Patients who received dexamethasone took significantly fewer posttreatment pain medications than those who received the placebo. Although there was a trend toward a reduction in the incidence of posttreatment pain for patients who received dexamethasone, the difference was not statistically significant.",
author = "Alan Liesinger and Marshall, {F. James} and Marshall, {J (Gordon)}",
year = "1993",
doi = "10.1016/S0099-2399(06)81039-3",
language = "English (US)",
volume = "19",
pages = "35--39",
journal = "Journal of Endodontics",
issn = "0099-2399",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Effect of variable doses of dexamethasone on posttreatment endodontic pain

AU - Liesinger, Alan

AU - Marshall, F. James

AU - Marshall, J (Gordon)

PY - 1993

Y1 - 1993

N2 - One hundred six patients with pretreatment pain presenting for endodontic treatment participated in a controlled double blind study. After root canal therapy, the patients were given an intraoral intramuscular injection of either a saline placebo or various dosages of dexamethasone. Posttreatment pain incidence and severity were evaluated at 4, 8, 24, 48, and 72 h. Injection of the various dosages of dexamethasone, taken as a group, was shown to significantly reduce the severity of pain at 4 and 8 h, and 0.07 to 0.09 mg/kg dosage alone significantly reduced pain at 8 h. Patients who received dexamethasone took significantly fewer posttreatment pain medications than those who received the placebo. Although there was a trend toward a reduction in the incidence of posttreatment pain for patients who received dexamethasone, the difference was not statistically significant.

AB - One hundred six patients with pretreatment pain presenting for endodontic treatment participated in a controlled double blind study. After root canal therapy, the patients were given an intraoral intramuscular injection of either a saline placebo or various dosages of dexamethasone. Posttreatment pain incidence and severity were evaluated at 4, 8, 24, 48, and 72 h. Injection of the various dosages of dexamethasone, taken as a group, was shown to significantly reduce the severity of pain at 4 and 8 h, and 0.07 to 0.09 mg/kg dosage alone significantly reduced pain at 8 h. Patients who received dexamethasone took significantly fewer posttreatment pain medications than those who received the placebo. Although there was a trend toward a reduction in the incidence of posttreatment pain for patients who received dexamethasone, the difference was not statistically significant.

UR - http://www.scopus.com/inward/record.url?scp=0027136311&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027136311&partnerID=8YFLogxK

U2 - 10.1016/S0099-2399(06)81039-3

DO - 10.1016/S0099-2399(06)81039-3

M3 - Article

VL - 19

SP - 35

EP - 39

JO - Journal of Endodontics

JF - Journal of Endodontics

SN - 0099-2399

IS - 1

ER -