Effect of soy isoflavone supplementation on menopausal quality of life

Paula Amato; Francene M. Steinberg; Michael J. Murray; Richard D. Lewis; Margaret A. Cramer; Stephen Barnes; Kenneth J. Ellis; Roman J. Shypailo; Joe Kennard Fraley; Karen L. Konzelmann; Joan G. Fischer; Colette Lasalle; Elliot O.Brian Smith; William W. Wong

doi:10.1097/GME.0b013e318275025e

Effect of soy isoflavone supplementation on menopausal quality of life

Paula Amato, Francene M. Steinberg, Michael J. Murray, Richard D. Lewis, Margaret A. Cramer, Stephen Barnes, Kenneth J. Ellis, Roman J. Shypailo, Joe Kennard Fraley, Karen L. Konzelmann, Joan G. Fischer, Colette Lasalle, Elliot O.Brian Smith, William W. Wong

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

Original language	English (US)
Pages (from-to)	443-447
Number of pages	5
Journal	Menopause
Volume	20
Issue number	4
DOIs	https://doi.org/10.1097/GME.0b013e318275025e
State	Published - Apr 2013

Keywords

Menopause
Quality of life
Soy isoflavones

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1097/GME.0b013e318275025e

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title = "Effect of soy isoflavone supplementation on menopausal quality of life",

abstract = "The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.",

keywords = "Menopause, Quality of life, Soy isoflavones",

author = "Paula Amato and Steinberg, {Francene M.} and Murray, {Michael J.} and Lewis, {Richard D.} and Cramer, {Margaret A.} and Stephen Barnes and Ellis, {Kenneth J.} and Shypailo, {Roman J.} and Fraley, {Joe Kennard} and Konzelmann, {Karen L.} and Fischer, {Joan G.} and Colette Lasalle and Smith, {Elliot O.Brian} and Wong, {William W.}",

year = "2013",

month = apr,

doi = "10.1097/GME.0b013e318275025e",

language = "English (US)",

volume = "20",

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journal = "Menopause",

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T1 - Effect of soy isoflavone supplementation on menopausal quality of life

AU - Amato, Paula

AU - Steinberg, Francene M.

AU - Murray, Michael J.

AU - Lewis, Richard D.

AU - Cramer, Margaret A.

AU - Barnes, Stephen

AU - Ellis, Kenneth J.

AU - Shypailo, Roman J.

AU - Fraley, Joe Kennard

AU - Konzelmann, Karen L.

AU - Fischer, Joan G.

AU - Lasalle, Colette

AU - Smith, Elliot O.Brian

AU - Wong, William W.

PY - 2013/4

Y1 - 2013/4

N2 - The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

AB - The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

KW - Menopause

KW - Quality of life

KW - Soy isoflavones

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JO - Menopause

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ER -

Effect of soy isoflavone supplementation on menopausal quality of life

Abstract

Keywords

ASJC Scopus subject areas

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