Effect of soy isoflavone supplementation on menopausal quality of life

Paula Amato, Francene M. Steinberg, Michael J. Murray, Richard D. Lewis, Margaret A. Cramer, Stephen Barnes, Kenneth J. Ellis, Roman J. Shypailo, Joe Kennard Fraley, Karen L. Konzelmann, Joan G. Fischer, Colette Lasalle, Elliot O.Brian Smith, William W. Wong

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

Original languageEnglish (US)
Pages (from-to)443-447
Number of pages5
JournalMenopause
Volume20
Issue number4
DOIs
StatePublished - Apr 2013

Keywords

  • Menopause
  • Quality of life
  • Soy isoflavones

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint

Dive into the research topics of 'Effect of soy isoflavone supplementation on menopausal quality of life'. Together they form a unique fingerprint.

Cite this