Abstract
Active E-rosette-forming lymphocytes were examined in patients with multiple sclerosis, patients with other neurological diseases, and patients with rheumatoid arthritis. Significantly fewer (P <0.01) active E rosettes were found in multiple sclerosis and RA patients than in controls. The lower levels of active E rosettes in MS could be enhanced by physiological levels of prostaglandins E1 and E2 (10-4 and 10-11 M). MS patients appar to have a circulating population of immature E-rosetting lymphocytes sensitive to modulation with prostaglandin E.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 159-167 |
| Number of pages | 9 |
| Journal | Clinical Immunology and Immunopathology |
| Volume | 22 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1982 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Pathology and Forensic Medicine
Cite this
Effect of prostaglandins and aspirin on active E-rosette formation in patients with multiple sclerosis. / Offner, Halina; Danneskiold-Samsøe, Bente; Dore-Duffy, Paula.
In: Clinical Immunology and Immunopathology, Vol. 22, No. 2, 1982, p. 159-167.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of prostaglandins and aspirin on active E-rosette formation in patients with multiple sclerosis
AU - Offner, Halina
AU - Danneskiold-Samsøe, Bente
AU - Dore-Duffy, Paula
PY - 1982
Y1 - 1982
N2 - Active E-rosette-forming lymphocytes were examined in patients with multiple sclerosis, patients with other neurological diseases, and patients with rheumatoid arthritis. Significantly fewer (P <0.01) active E rosettes were found in multiple sclerosis and RA patients than in controls. The lower levels of active E rosettes in MS could be enhanced by physiological levels of prostaglandins E1 and E2 (10-4 and 10-11 M). MS patients appar to have a circulating population of immature E-rosetting lymphocytes sensitive to modulation with prostaglandin E.
AB - Active E-rosette-forming lymphocytes were examined in patients with multiple sclerosis, patients with other neurological diseases, and patients with rheumatoid arthritis. Significantly fewer (P <0.01) active E rosettes were found in multiple sclerosis and RA patients than in controls. The lower levels of active E rosettes in MS could be enhanced by physiological levels of prostaglandins E1 and E2 (10-4 and 10-11 M). MS patients appar to have a circulating population of immature E-rosetting lymphocytes sensitive to modulation with prostaglandin E.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020082448&partnerID=8YFLogxK
U2 - 10.1016/0090-1229(82)90034-4
DO - 10.1016/0090-1229(82)90034-4
M3 - Article
C2 - 6286189
AN - SCOPUS:0020082448
VL - 22
SP - 159
EP - 167
JO - Clinical Immunology
JF - Clinical Immunology
SN - 1521-6616
IS - 2
ER -