Effect of pilocarpine ocular therapeutic systems on diurnal control of intraocular pressure

F. T. Fraunfelder, J. W. Shell, S. F. Herbst

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The pilocarpine ocular therapeutic system is an innovative ocular drug delivery system which releases pilocarpine into the tear film at a constant rate of 20 μg/hr or 40 μg/hr. The system was evaluated in 22 hospitalized patients with bilateral open angle glaucoma to determine its ability to control ocular pressure throughout the diurnal interval. Only the right eye of each patient was treated with the pilocarpine ocular therapeutic system; the other eye served as a control. Twelve pressure measurements were made with a noncontact tonometer over a 34 hour test period. In general, the pilocarpine ocular therapeutic system provided satisfactory around the clock control of intraocular pressure and was well tolerated by the patients.

Original languageEnglish (US)
Pages (from-to)1031-1039
Number of pages9
JournalAnnals of Ophthalmology
Volume8
Issue number9
StatePublished - Dec 1 1976

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Effect of pilocarpine ocular therapeutic systems on diurnal control of intraocular pressure'. Together they form a unique fingerprint.

  • Cite this