Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome

Judith Levine Ross, Lauren Myerson Long, Marilyn Skerda, Fernando Cassorla, David Kurtz, Donald (Lynn) Loriaux, Gordon B. Cutler

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

We randomly assigned 16 girls with Turner syndrome, age 5 to 15 years, to receive treatment with 100 ng/kg/day ethinyl estradiol or placebo for 6 months, with crossover after a 2-month interim period. We assessed growth by measurement of the 4-week lower leg growth rate and by height velocity. Bone age was determined at the beginning and end of treatment. Growth rate during ethinyl estradiol treatment was approximately 70% greater than during placebo (P

Original languageEnglish (US)
Pages (from-to)950-953
Number of pages4
JournalThe Journal of Pediatrics
Volume109
Issue number6
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Turner Syndrome
Estradiol
Ethinyl Estradiol
Growth
Placebos
Leg
Therapeutics
Bone and Bones

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome. / Ross, Judith Levine; Long, Lauren Myerson; Skerda, Marilyn; Cassorla, Fernando; Kurtz, David; Loriaux, Donald (Lynn); Cutler, Gordon B.

In: The Journal of Pediatrics, Vol. 109, No. 6, 1986, p. 950-953.

Research output: Contribution to journalArticle

Ross, Judith Levine ; Long, Lauren Myerson ; Skerda, Marilyn ; Cassorla, Fernando ; Kurtz, David ; Loriaux, Donald (Lynn) ; Cutler, Gordon B. / Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome. In: The Journal of Pediatrics. 1986 ; Vol. 109, No. 6. pp. 950-953.
@article{a5aa8e19028743ae9783c6607076e43d,
title = "Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome",
abstract = "We randomly assigned 16 girls with Turner syndrome, age 5 to 15 years, to receive treatment with 100 ng/kg/day ethinyl estradiol or placebo for 6 months, with crossover after a 2-month interim period. We assessed growth by measurement of the 4-week lower leg growth rate and by height velocity. Bone age was determined at the beginning and end of treatment. Growth rate during ethinyl estradiol treatment was approximately 70{\%} greater than during placebo (P",
author = "Ross, {Judith Levine} and Long, {Lauren Myerson} and Marilyn Skerda and Fernando Cassorla and David Kurtz and Loriaux, {Donald (Lynn)} and Cutler, {Gordon B.}",
year = "1986",
doi = "10.1016/S0022-3476(86)80274-8",
language = "English (US)",
volume = "109",
pages = "950--953",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome

AU - Ross, Judith Levine

AU - Long, Lauren Myerson

AU - Skerda, Marilyn

AU - Cassorla, Fernando

AU - Kurtz, David

AU - Loriaux, Donald (Lynn)

AU - Cutler, Gordon B.

PY - 1986

Y1 - 1986

N2 - We randomly assigned 16 girls with Turner syndrome, age 5 to 15 years, to receive treatment with 100 ng/kg/day ethinyl estradiol or placebo for 6 months, with crossover after a 2-month interim period. We assessed growth by measurement of the 4-week lower leg growth rate and by height velocity. Bone age was determined at the beginning and end of treatment. Growth rate during ethinyl estradiol treatment was approximately 70% greater than during placebo (P

AB - We randomly assigned 16 girls with Turner syndrome, age 5 to 15 years, to receive treatment with 100 ng/kg/day ethinyl estradiol or placebo for 6 months, with crossover after a 2-month interim period. We assessed growth by measurement of the 4-week lower leg growth rate and by height velocity. Bone age was determined at the beginning and end of treatment. Growth rate during ethinyl estradiol treatment was approximately 70% greater than during placebo (P

UR - http://www.scopus.com/inward/record.url?scp=0023035775&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023035775&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(86)80274-8

DO - 10.1016/S0022-3476(86)80274-8

M3 - Article

C2 - 3537251

AN - SCOPUS:0023035775

VL - 109

SP - 950

EP - 953

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 6

ER -