Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients

Susan Rowell, Ronald R. Barbosa, Brian S. Diggs, Martin Schreiber, Trauma Outcomes Group The Trauma Outcomes Group

    Research output: Contribution to journalArticle

    34 Citations (Scopus)

    Abstract

    Background: Recent data suggest that massively transfused patients have lower mortality rates when high ratios (>1:2) of plasma or platelets to red blood cells (RBCs) are used. Blunt and penetrating trauma patients have different injury patterns and may respond differently to resuscitation. This study was performed to determine whether mortality after high product ratio massive transfusion is different in blunt and penetrating trauma patients. Methods: Patients receiving 10 or more units of RBCs in the first 24 hours after admission to one of 23 Level I trauma centers were analyzed. Baseline physiologic and biochemical data were obtained. Univariate and logistic regression analyses were performed. Adjusted mortality in patients receiving high (≥1:2) and low (

    Original languageEnglish (US)
    JournalJournal of Trauma - Injury, Infection and Critical Care
    Volume71
    Issue number2 SUPPL. 3
    DOIs
    StatePublished - Aug 2011

    Fingerprint

    Mortality
    Wounds and Injuries
    Erythrocytes
    Trauma Centers
    Resuscitation
    Blood Platelets
    Logistic Models
    Regression Analysis

    Keywords

    • Massive transfusion
    • Mechanism
    • Mortality
    • Trauma

    ASJC Scopus subject areas

    • Surgery
    • Critical Care and Intensive Care Medicine

    Cite this

    Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients. / Rowell, Susan; Barbosa, Ronald R.; Diggs, Brian S.; Schreiber, Martin; The Trauma Outcomes Group, Trauma Outcomes Group.

    In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 71, No. 2 SUPPL. 3, 08.2011.

    Research output: Contribution to journalArticle

    Rowell, Susan ; Barbosa, Ronald R. ; Diggs, Brian S. ; Schreiber, Martin ; The Trauma Outcomes Group, Trauma Outcomes Group. / Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients. In: Journal of Trauma - Injury, Infection and Critical Care. 2011 ; Vol. 71, No. 2 SUPPL. 3.
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