EFFECT OF FLUORINE SUBSTITUTION ON THE ANODIC OXIDATION OF CATECHOLAMINES AND AMINO ACIDS.

Margaret E. Rice, Bita Moghaddam, Cyrus R. Creveling, Bita Moghaddam

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The electrochemical behavior of the 2-, 5-, and 6-fluoro analogues of dopamine (DA), norepinephrine (NE), and (3,4-dihydroxyphenyl)alanine (DOPA) have been determined by cyclic voltammetry and by measuring fluoride release during bulk oxidations. The 6-fluoro analogue in each series of compounds is the most easily oxidized and appears to result from a 2-electron process rather than the four-electron process (the ECE pathway) for the parent catecholamines or catecholamino acid.

Original languageEnglish (US)
Pages (from-to)1534-1538
Number of pages5
JournalAnalytical Chemistry
Volume59
Issue number11
StatePublished - Jun 1 1987
Externally publishedYes

Fingerprint

Fluorine
Anodic oxidation
Catecholamines
Substitution reactions
Amino Acids
Electrons
Fluorides
Alanine
Cyclic voltammetry
Dopamine
Norepinephrine
Oxidation
Acids

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

EFFECT OF FLUORINE SUBSTITUTION ON THE ANODIC OXIDATION OF CATECHOLAMINES AND AMINO ACIDS. / Rice, Margaret E.; Moghaddam, Bita; Creveling, Cyrus R.; Moghaddam, Bita.

In: Analytical Chemistry, Vol. 59, No. 11, 01.06.1987, p. 1534-1538.

Research output: Contribution to journalArticle

Rice, Margaret E. ; Moghaddam, Bita ; Creveling, Cyrus R. ; Moghaddam, Bita. / EFFECT OF FLUORINE SUBSTITUTION ON THE ANODIC OXIDATION OF CATECHOLAMINES AND AMINO ACIDS. In: Analytical Chemistry. 1987 ; Vol. 59, No. 11. pp. 1534-1538.
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