Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami; David D. Brandon; D. Lynn Loriaux; Mortimer B. Lipsett

doi:10.1016/0022-4731(80)90147-8

Effect of cortisol, T₃ and T₄ on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami, David D. Brandon, D. Lynn Loriaux, Mortimer B. Lipsett

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T₃, and T₄, were not accompanied by alterations of the binding capacity for [³H]dexamethasone in leukocytes.

Original language	English (US)
Pages (from-to)	1125-1127
Number of pages	3
Journal	Journal of Steroid Biochemistry
Volume	13
Issue number	9
DOIs	https://doi.org/10.1016/0022-4731(80)90147-8
State	Published - 1980
Externally published	Yes

Keywords

T, thyroxine
cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione
dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione
t, tri-iodothyronine

ASJC Scopus subject areas

Biochemistry
Endocrinology

Access to Document

10.1016/0022-4731(80)90147-8

Cite this

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title = "Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes",

abstract = "The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.",

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author = "Tohru Murakami and Brandon, {David D.} and {Lynn Loriaux}, D. and Lipsett, {Mortimer B.}",

year = "1980",

doi = "10.1016/0022-4731(80)90147-8",

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pages = "1125--1127",

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T1 - Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

AU - Murakami, Tohru

AU - Brandon, David D.

AU - Lynn Loriaux, D.

AU - Lipsett, Mortimer B.

PY - 1980

Y1 - 1980

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AB - The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.

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KW - cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione

KW - dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione

KW - t, tri-iodothyronine

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