Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami, David D. Brandon, D. Lynn Loriaux, Mortimer B. Lipsett

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.

Original languageEnglish (US)
Pages (from-to)1125-1127
Number of pages3
JournalJournal of Steroid Biochemistry
Volume13
Issue number9
DOIs
StatePublished - Jan 1 1980

Keywords

  • T, thyroxine
  • cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione
  • dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • t, tri-iodothyronine

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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