Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami; David D. Brandon; D. Lynn Loriaux; Mortimer B. Lipsett

doi:10.1016/0022-4731(80)90147-8

Effect of cortisol, T₃ and T₄ on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami, David D. Brandon, D. Lynn Loriaux, Mortimer B. Lipsett

Endocrinology

Research output: Contribution to journal › Article

9 Scopus citations

Abstract

The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T₃, and T₄, were not accompanied by alterations of the binding capacity for [³H]dexamethasone in leukocytes.

Original language	English (US)
Pages (from-to)	1125-1127
Number of pages	3
Journal	Journal of Steroid Biochemistry
Volume	13
Issue number	9
DOIs	https://doi.org/10.1016/0022-4731(80)90147-8
State	Published - Jan 1 1980

Keywords

T, thyroxine
cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione
dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione
t, tri-iodothyronine

ASJC Scopus subject areas

Biochemistry
Endocrinology

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Murakami, T., Brandon, D. D., Lynn Loriaux, D., & Lipsett, M. B. (1980). Effect of cortisol, T₃ and T₄ on the glucocorticoid receptor concentration in leukocytes. Journal of Steroid Biochemistry, 13(9), 1125-1127. https://doi.org/10.1016/0022-4731(80)90147-8

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