Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami; David D. Brandon; D. Lynn Loriaux; Mortimer B. Lipsett

doi:10.1016/0022-4731(80)90147-8

Effect of cortisol, T₃ and T₄ on the glucocorticoid receptor concentration in leukocytes

Tohru Murakami, David D. Brandon, D. Lynn Loriaux, Mortimer B. Lipsett

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T₃, and T₄, were not accompanied by alterations of the binding capacity for [³H]dexamethasone in leukocytes.

Original language	English (US)
Pages (from-to)	1125-1127
Number of pages	3
Journal	Journal of Steroid Biochemistry
Volume	13
Issue number	9
DOIs	https://doi.org/10.1016/0022-4731(80)90147-8
State	Published - Jan 1 1980
Externally published	Yes

Keywords

T, thyroxine
cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione
dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione
t, tri-iodothyronine

ASJC Scopus subject areas

Biochemistry
Endocrinology

Access to Document

10.1016/0022-4731(80)90147-8

Cite this

@article{4968b705e16244399a3a160753fc74e3,

title = "Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes",

abstract = "The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.",

keywords = "T, thyroxine, cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione, dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione, t, tri-iodothyronine",

author = "Tohru Murakami and Brandon, {David D.} and {Lynn Loriaux}, D. and Lipsett, {Mortimer B.}",

year = "1980",

month = jan,

day = "1",

doi = "10.1016/0022-4731(80)90147-8",

language = "English (US)",

volume = "13",

pages = "1125--1127",

journal = "Journal of Steroid Biochemistry and Molecular Biology",

issn = "0960-0760",

publisher = "Elsevier Limited",

number = "9",

}

TY - JOUR

T1 - Effect of cortisol, T3 and T4 on the glucocorticoid receptor concentration in leukocytes

AU - Murakami, Tohru

AU - Brandon, David D.

AU - Lynn Loriaux, D.

AU - Lipsett, Mortimer B.

PY - 1980/1/1

Y1 - 1980/1/1

N2 - The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.

AB - The glucocorticoid receptor concentration in goat leukocytes was measured before and during administration of ACTH, sodium l-thyroxine, or 6-n-propylthiouracil. The resultant changes in the concentrations of cortisol, T3, and T4, were not accompanied by alterations of the binding capacity for [3H]dexamethasone in leukocytes.

KW - T, thyroxine

KW - cortisol, 11β,17,21-trihydroxy-4-pregnene-3,20-dione

KW - dexamethasone (Dex), 9α-fluro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione

KW - t, tri-iodothyronine

UR - http://www.scopus.com/inward/record.url?scp=0019230853&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019230853&partnerID=8YFLogxK

U2 - 10.1016/0022-4731(80)90147-8

DO - 10.1016/0022-4731(80)90147-8

M3 - Article

C2 - 6252389

AN - SCOPUS:0019230853

VL - 13

SP - 1125

EP - 1127

JO - Journal of Steroid Biochemistry and Molecular Biology

JF - Journal of Steroid Biochemistry and Molecular Biology

SN - 0960-0760

IS - 9

ER -