Effect of cognitive rehabilitation on outcomes for persons with traumatic brain injury: A systematic review

Nancy Carney, Randall M. Chesnut, Hugo Maynard, N. Clay Mann, Patricia Patterson, Mark Helfand

Research output: Contribution to journalArticle

183 Scopus citations


We evaluated evidence for the effectiveness of cognitive rehabilitation methods to improve outcomes for persons with traumatic brain injury (TBI). A search of MEDLINE, HealthSTAR, CINAHL, PsycINFO, and the Cochrane Library produced 600 potential references. Thirty-two studies met predetermined inclusion criteria and were abstracted; data from 24 were placed into evidence tables. Two randomized controlled trials and one observational study provided evidence that specific forms of cognitive rehabilitation reduce memory failures and anxiety, and improve self-concept and interpersonal relationships for persons with TBI. The durability and clinical relevance of these findings is not established. Future research utilizing control groups and multivariate analysis must incorparate subject variability and must include standard definitions of the intervention and relevant outcome measures that reflect health and function.

Original languageEnglish (US)
Pages (from-to)277-307
Number of pages31
JournalJournal of Head Trauma Rehabilitation
Issue number3
Publication statusPublished - Jun 1999



  • Cognitive rehabilitation
  • Evidence based
  • Systematic review

ASJC Scopus subject areas

  • Rehabilitation
  • Clinical Neurology
  • Health Professions(all)

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