Effect of burn injury on the kinetics of in vivo polymorphonuclear neutrophil (PMN) chemotaxis to staphylococcus aureus

Anthony A. Meyer, Anne Manktelow, Donald Trunkey

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This study investigated the effect of time after burn injury on the kinetics of polymorphonuclear neutrophil (PMN) chemotaxis to Staphylococcus aureus. Rats with 30% body surface area back burns, and nonburned control rats, received several identical inocula ofS aureus 3, 6, and 10 days after injury, and in vivo chemotaxis was measured by tissue myeloperoxidase at varying intervals. Animals six and ten days postburn had a delay, as well as a decrease, in maximal chemotactic response. This delay in response appears to be another mechanism by which PMN chemotaxis is affected by burn injury.

Original languageEnglish (US)
Pages (from-to)465-468
Number of pages4
JournalJournal of Burn Care and Rehabilitation
Volume7
Issue number6
StatePublished - 1986
Externally publishedYes

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Chemotaxis
Staphylococcus aureus
Neutrophils
Wounds and Injuries
Body Surface Area
Peroxidase

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Clinical Psychology
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Emergency Medicine
  • Rehabilitation
  • Surgery
  • Nursing(all)
  • Health Professions(all)

Cite this

Effect of burn injury on the kinetics of in vivo polymorphonuclear neutrophil (PMN) chemotaxis to staphylococcus aureus. / Meyer, Anthony A.; Manktelow, Anne; Trunkey, Donald.

In: Journal of Burn Care and Rehabilitation, Vol. 7, No. 6, 1986, p. 465-468.

Research output: Contribution to journalArticle

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