TY - JOUR
T1 - Effect of burn injury on the kinetics of in vivo polymorphonuclear neutrophil (PMN) chemotaxis to staphylococcus aureus
AU - Meyer, Anthony A.
AU - Manktelow, Anne
AU - Trunkey, Donald D.
PY - 1986
Y1 - 1986
N2 - This study investigated the effect of time after burn injury on the kinetics of polymorphonuclear neutrophil (PMN) chemotaxis to Staphylococcus aureus. Rats with 30% body surface area back burns, and nonburned control rats, received several identical inocula ofS aureus 3, 6, and 10 days after injury, and in vivo chemotaxis was measured by tissue myeloperoxidase at varying intervals. Animals six and ten days postburn had a delay, as well as a decrease, in maximal chemotactic response. This delay in response appears to be another mechanism by which PMN chemotaxis is affected by burn injury.
AB - This study investigated the effect of time after burn injury on the kinetics of polymorphonuclear neutrophil (PMN) chemotaxis to Staphylococcus aureus. Rats with 30% body surface area back burns, and nonburned control rats, received several identical inocula ofS aureus 3, 6, and 10 days after injury, and in vivo chemotaxis was measured by tissue myeloperoxidase at varying intervals. Animals six and ten days postburn had a delay, as well as a decrease, in maximal chemotactic response. This delay in response appears to be another mechanism by which PMN chemotaxis is affected by burn injury.
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U2 - 10.1097/00004630-198611000-00003
DO - 10.1097/00004630-198611000-00003
M3 - Article
C2 - 3429477
AN - SCOPUS:0022839730
SN - 0273-8481
VL - 7
SP - 465
EP - 468
JO - Journal of Burn Care and Rehabilitation
JF - Journal of Burn Care and Rehabilitation
IS - 6
ER -