Echocardiographic detection and management of patent ductus arteriosus in neonates with respiratory distress syndrome

A two and one half year prospective study

S. J. Goldberg, H. D. Allen, David Sahn

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A prospective 2 1/2 year study of 50 infants with combined respiratory distress syndrome (RDS) and patent ductus arteriosus (PDA) was undertaken to determine whether echocardiographic measurements combined with clinical assessment could be used to select those infants who needed cardiac treatment. From a pilot study, criteria were adopted to use digoxin in the treatment of infants with evidence of congestive cardiac failure and/or a left atrial dimension 1.5 times normal size, and to ligate the PDA in those with unremitting congestive cardiac failure and a left atrial dimension persistently twice normal. Left atrial, left ventricular, and aortic dimension, left atrial to aortic ratio, and mean Vcf were echocardiographically determined. Forty-six per cent of the 50 infants with PDA required digoxin administration, and 18 per cent of the total group was operated. The long-term mortality for the total group was 12 per cent (6 of 50) and mortality was 33 per cent (3 of 9) for the operated group. Results showed that absolute left atrial dimension, particularly if recorded in two dimensions, most accurately predicted those infants who would develop congestive cardiac failure or failure that would become medically unmanageable.

Original languageEnglish (US)
Pages (from-to)161-169
Number of pages9
JournalJournal of Clinical Ultrasound
Volume5
Issue number3
StatePublished - 1977
Externally publishedYes

Fingerprint

Patent Ductus Arteriosus
patents
Newborn Infant
Prospective Studies
Heart Failure
mortality
Digoxin
Mortality
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Acoustics and Ultrasonics
  • Radiological and Ultrasound Technology

Cite this

Echocardiographic detection and management of patent ductus arteriosus in neonates with respiratory distress syndrome : A two and one half year prospective study. / Goldberg, S. J.; Allen, H. D.; Sahn, David.

In: Journal of Clinical Ultrasound, Vol. 5, No. 3, 1977, p. 161-169.

Research output: Contribution to journalArticle

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