Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles

K. A V Zubris, Onkar V. Khullar, Aaron P. Griset, Summer Gibbs, John V. Frangioni, Yolonda L. Colson, Mark W. Grinstaff

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Flying south for the winter! Polymeric nanoparticles were synthesized using either a photoinduced or base-catalyzed free-radical polymerization method. The particles (1 = 5 0 nm), loaded with a dye (IR-786), were observed to migrate over 20 cm to the sentinel lymph node after injection in a live pig. (Chemical Equation Presented)

Original languageEnglish (US)
Pages (from-to)1435-1438
Number of pages4
JournalChemMedChem
Volume5
Issue number9
DOIs
StatePublished - Sep 3 2010
Externally publishedYes

Fingerprint

Animal Migration
Lymph
Free radical polymerization
Polymerization
Nanoparticles
Free Radicals
Animals
Coloring Agents
Swine
Injections
IR-786
Sentinel Lymph Node
cyhalothrin

Keywords

  • Drug delivery
  • Imaging agents
  • Nanoparticles
  • Polymerization
  • Redox chemistry

ASJC Scopus subject areas

  • Molecular Medicine
  • Organic Chemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Zubris, K. A. V., Khullar, O. V., Griset, A. P., Gibbs, S., Frangioni, J. V., Colson, Y. L., & Grinstaff, M. W. (2010). Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. ChemMedChem, 5(9), 1435-1438. https://doi.org/10.1002/cmdc.201000250

Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. / Zubris, K. A V; Khullar, Onkar V.; Griset, Aaron P.; Gibbs, Summer; Frangioni, John V.; Colson, Yolonda L.; Grinstaff, Mark W.

In: ChemMedChem, Vol. 5, No. 9, 03.09.2010, p. 1435-1438.

Research output: Contribution to journalArticle

Zubris, KAV, Khullar, OV, Griset, AP, Gibbs, S, Frangioni, JV, Colson, YL & Grinstaff, MW 2010, 'Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles', ChemMedChem, vol. 5, no. 9, pp. 1435-1438. https://doi.org/10.1002/cmdc.201000250
Zubris, K. A V ; Khullar, Onkar V. ; Griset, Aaron P. ; Gibbs, Summer ; Frangioni, John V. ; Colson, Yolonda L. ; Grinstaff, Mark W. / Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. In: ChemMedChem. 2010 ; Vol. 5, No. 9. pp. 1435-1438.
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