Abstract
BACKGROUND AND OBJECTIVE: Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period. PATIENTS AND METHODS: A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life. RESULTS: Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Immediate laser photocoagulation of the avascular retina and vitrectomy for traction retinal detachment within several days to weeks improved or stabilized the retinal anatomy in all cases. CONCLUSIONS: This series describes clinical features in APVR in premature infants and suggests that early diagnosis and intervention may mitigate the typical aggressive course and poor prognosis of this condition. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:201-207.].
| Original language | English (US) |
|---|---|
| Pages (from-to) | 201-207 |
| Number of pages | 7 |
| Journal | Ophthalmic surgery, lasers & imaging retina |
| Volume | 50 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2019 |
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ASJC Scopus subject areas
- Surgery
- Ophthalmology
Cite this
Early Diagnosis and Management of Aggressive Posterior Vitreoretinopathy Presenting in Premature Neonates. / Gupta, Mrinali P.; Yonekawa, Yoshihiro; Campbell, John; Rusu, Irene; Zahid, Sarwar; Patel, Samir N.; Chau, Felix; Jonas, Karyn E.; Oltra, Erica; Orlin, Anton; Chang, Jonathan; Horowitz, Jason; Abramson, David H.; Marr, Brian; Capone, Antonio; Paul Chan, R. V.
In: Ophthalmic surgery, lasers & imaging retina, Vol. 50, No. 4, 01.04.2019, p. 201-207.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Early Diagnosis and Management of Aggressive Posterior Vitreoretinopathy Presenting in Premature Neonates
AU - Gupta, Mrinali P.
AU - Yonekawa, Yoshihiro
AU - Campbell, John
AU - Rusu, Irene
AU - Zahid, Sarwar
AU - Patel, Samir N.
AU - Chau, Felix
AU - Jonas, Karyn E.
AU - Oltra, Erica
AU - Orlin, Anton
AU - Chang, Jonathan
AU - Horowitz, Jason
AU - Abramson, David H.
AU - Marr, Brian
AU - Capone, Antonio
AU - Paul Chan, R. V.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - BACKGROUND AND OBJECTIVE: Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period. PATIENTS AND METHODS: A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life. RESULTS: Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Immediate laser photocoagulation of the avascular retina and vitrectomy for traction retinal detachment within several days to weeks improved or stabilized the retinal anatomy in all cases. CONCLUSIONS: This series describes clinical features in APVR in premature infants and suggests that early diagnosis and intervention may mitigate the typical aggressive course and poor prognosis of this condition. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:201-207.].
AB - BACKGROUND AND OBJECTIVE: Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period. PATIENTS AND METHODS: A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life. RESULTS: Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Immediate laser photocoagulation of the avascular retina and vitrectomy for traction retinal detachment within several days to weeks improved or stabilized the retinal anatomy in all cases. CONCLUSIONS: This series describes clinical features in APVR in premature infants and suggests that early diagnosis and intervention may mitigate the typical aggressive course and poor prognosis of this condition. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:201-207.].
UR - http://www.scopus.com/inward/record.url?scp=85065074003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065074003&partnerID=8YFLogxK
U2 - 10.3928/23258160-20190401-01
DO - 10.3928/23258160-20190401-01
M3 - Article
C2 - 30998240
AN - SCOPUS:85065074003
VL - 50
SP - 201
EP - 207
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
SN - 2325-8160
IS - 4
ER -