Dystrophic calcification of silicone scleral buckling implant materials

R. J. Brockhurst, R. C. Ward, P. Lou, D. Ormerod, D. Albert

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

In six patients, removal of solid silicone scleral buckling implant materials that had been in place between eight and 21 years disclosed gray- white deposits firmly adherent to the silicone. Four of the six patients had culture-proven infections, whereas two had no evidence of infection and had negative cultures. One of these two patients, however, had intermittent pain, which was the indication for removal of the implant. Analysis of the deposits disclosed that they were calcium phosphate. The exact mechanism responsible for the calcification on the silicone material is unknown. Dystrophic calcification can occur without infection in injured tissue wherein extracellular deposits of devitalized cells, blood cells, and lipids may act as a nidus for calcification. In the presence of infection, bacteria may serve as such a nidus. Additionally, it is possible that biofilm produced by the bacteria had a role in the deposition of calcium phosphate, as well as in its firm adhesion to the silicone materials. We considered the possibility of similar deposits developing on intraocular silicone lenses.

Original languageEnglish (US)
Pages (from-to)524-529
Number of pages6
JournalAmerican journal of ophthalmology
Volume115
Issue number4
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Ophthalmology

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