Dopamine agonist therapy induces significant recovery of HPA axis function in prolactinomas independent of tumor size: a large single center experience

Christine (Chris) Yedinak; Isabelle Cetas; Alp Ozpinar; Shirley McCartney; Aclan Dogan; Maria Fleseriu

doi:10.1007/s12020-016-1042-2

Dopamine agonist therapy induces significant recovery of HPA axis function in prolactinomas independent of tumor size: a large single center experience

Christine (Chris) Yedinak, Isabelle Cetas, Alp Ozpinar, Shirley McCartney, Aclan Dogan, Maria Fleseriu

Neurosurgery

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Our objective was to compare prevalence and rates of recovery of hypothalamic–pituitary–adrenal axis dysfunction in prolactinoma patients before and after dopamine agonist therapy with nonfunctioning pituitary adenoma patients pre-transsphenoidal and post-transsphenoidal surgery. We retrospectively compared hypothalamic–pituitary–adrenal axis function in patients with prolactinomas naïve to dopamine agonist therapy with a cohort of nonfunctioning pituitary adenoma patients matched for gender and tumor size by classification (n = 57; 30 male/27 female; 27 microadenoma/30 macroadenoma). Patients with

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Endocrine
DOIs	https://doi.org/10.1007/s12020-016-1042-2
State	Accepted/In press - Jul 26 2016

Keywords

Adrenal insufficiency
Hypopituitarism
Nonfunctioning pituitary adenomas
Prolactinomas
Recovery of adrenal function

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1007/s12020-016-1042-2

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abstract = "Our objective was to compare prevalence and rates of recovery of hypothalamic–pituitary–adrenal axis dysfunction in prolactinoma patients before and after dopamine agonist therapy with nonfunctioning pituitary adenoma patients pre-transsphenoidal and post-transsphenoidal surgery. We retrospectively compared hypothalamic–pituitary–adrenal axis function in patients with prolactinomas na{\"i}ve to dopamine agonist therapy with a cohort of nonfunctioning pituitary adenoma patients matched for gender and tumor size by classification (n = 57; 30 male/27 female; 27 microadenoma/30 macroadenoma). Patients with ",

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AU - Ozpinar, Alp

AU - McCartney, Shirley

AU - Dogan, Aclan

AU - Fleseriu, Maria

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Dopamine agonist therapy induces significant recovery of HPA axis function in prolactinomas independent of tumor size: a large single center experience

Abstract

Keywords

ASJC Scopus subject areas

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