Donor Unrestricted T Cells: Linking innate and adaptive immunity

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Donor Unrestricted T Cells (DURTs) are characterized by their use of antigen presentation molecules that are often invariant. As these cells recognize diverse mycobacterial antigens, often found in BCG, these cells have the potential to either serve as targets for vaccination, or as a means to enable the induction of traditional T and B cell immunity. Here, we will review specific DURT family members, and their relationship to BCG.

Original languageEnglish (US)
Pages (from-to)7295-7299
Number of pages5
JournalVaccine
Volume39
Issue number50
DOIs
StatePublished - Dec 8 2021

Keywords

  • BCG
  • CD1
  • Donor Unrestricted T cell
  • Gamma Delta
  • HLA-E
  • MR1

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Donor Unrestricted T Cells: Linking innate and adaptive immunity'. Together they form a unique fingerprint.

Cite this