Does PSADT after radical prostatectomy correlate with overall survival?-A report from the SEARCH database group

Anna E. Teeter, Joseph C. Presti, William J. Aronson, Martha K. Terris, Christopher J. Kane, Christopher Amling, Stephen J. Freedland

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives: To examine the correlation between the prostate-specific antigen doubling time (PSADT) and overall survival (OS) and among men in the SEARCH database (an older, racially diverse cohort undergoing RP at multiple Veterans Affairs medical centers). Previous studies largely performed at tertiary care centers with relatively young, racially homogenous cohorts found a short PSADT on recurrence after RP portended a poor prognosis. Methods: We performed a Cox proportional hazards analysis to examine the correlation between postrecurrence PSADT and the interval from recurrence to OS and prostate cancer-specific mortality among 345 men in the SEARCH database who had undergone RP from 1988 to 2008. We examined the PSADT as a categorical variable using the clinically significant cutpoints of

Original languageEnglish (US)
Pages (from-to)149-153
Number of pages5
JournalUrology
Volume77
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

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Prostate-Specific Antigen
Prostatectomy
Databases
Survival
Recurrence
Veterans
Tertiary Care Centers
Prostatic Neoplasms
Mortality

ASJC Scopus subject areas

  • Urology

Cite this

Teeter, A. E., Presti, J. C., Aronson, W. J., Terris, M. K., Kane, C. J., Amling, C., & Freedland, S. J. (2011). Does PSADT after radical prostatectomy correlate with overall survival?-A report from the SEARCH database group. Urology, 77(1), 149-153. https://doi.org/10.1016/j.urology.2010.04.071

Does PSADT after radical prostatectomy correlate with overall survival?-A report from the SEARCH database group. / Teeter, Anna E.; Presti, Joseph C.; Aronson, William J.; Terris, Martha K.; Kane, Christopher J.; Amling, Christopher; Freedland, Stephen J.

In: Urology, Vol. 77, No. 1, 01.2011, p. 149-153.

Research output: Contribution to journalArticle

Teeter, Anna E. ; Presti, Joseph C. ; Aronson, William J. ; Terris, Martha K. ; Kane, Christopher J. ; Amling, Christopher ; Freedland, Stephen J. / Does PSADT after radical prostatectomy correlate with overall survival?-A report from the SEARCH database group. In: Urology. 2011 ; Vol. 77, No. 1. pp. 149-153.
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AU - Presti, Joseph C.

AU - Aronson, William J.

AU - Terris, Martha K.

AU - Kane, Christopher J.

AU - Amling, Christopher

AU - Freedland, Stephen J.

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