Does peritoneal mobilization increase laparoscopic acidosis?

Adrian E. Ortega, Nicole Baril, Salvador Rivera Lara, Timothy Liem, Gary Anthone, Robert W. Beart

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    PURPOSE: It was hypothesized that laparoscopic colon surgery may be associated with increased absorption of CO2 resulting from mobilization of lateral peritoneal reflections. METHODS: Six pigs underwent laparotomy with removal of a measured quadrant of peritoneum before insufflation to 15 mmHg with CO2. Six paired control animals also underwent insufflation with CO2 to 15 mmHg. Measurements of the end-tidal CO2 (PetCO2), arterial blood gas analysis for CO2(PaCO2), and pH were performed before insufflation, at 5 and 10 minutes following insufflation, then at successive 15-minute intervals for a total of two hours, and 15 minutes following desufflation. No attempt was made to correct the hypercarbia by increasing minute ventilation. RESULTS: PaCO2 reached its maximum level at two hours with values of 70.77±5.54 mmHg and 64.62±5.18 mmHg in the peritonectomized and control groups, respectively. PetCO2 also peaked at two hours to 60±13 mmHg for the study group and 54±11 mmHg for controls. pH reached its nadir at two hours, falling from a baseline of 7.45±0.08 to 7.23±0.09 in the study group, and from 7.42±0.04 to 7.24 ±0.04 in the control group. There were no statistically significant differences between the two groups for any of the parameters measured at each time interval. CONCLUSIONS: The hypothesis that peritonectomy produces greater CO2 absorption during CO2 pneumoperitoneum was disproved under these experimental conditions.

    Original languageEnglish (US)
    Pages (from-to)1296-1300
    Number of pages5
    JournalDiseases of the Colon & Rectum
    Issue number12
    StatePublished - Dec 1 1995


    • Carbon dioxide
    • Hypercarbia
    • Laparoscopy

    ASJC Scopus subject areas

    • Gastroenterology

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    Ortega, A. E., Baril, N., Lara, S. R., Liem, T., Anthone, G., & Beart, R. W. (1995). Does peritoneal mobilization increase laparoscopic acidosis? Diseases of the Colon & Rectum, 38(12), 1296-1300.