Does fibromyalgia influence symptom bother from pelvic organ prolapse?

Kerrie Adams, Blake Osmundsen, W. Thomas Gregory

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Introduction and hypothesis: Determine if women with fibromyalgia report increased bother from pelvic organ prolapse compared with women without fibromyalgia. Methods: We performed a cross-sectional study of women with symptomatic prolapse on consultation with a private urogynecology practice within a 46-month period. After matching for age, women with a diagnosis of fibromyalgia were compared with a reference group of women without fibromyalgia. Demographic, POPQ examination, medical history, and pelvic floor symptom data (PFDI, PFIQ, and PISQ-12) were collected. Our primary outcomewas to compare the mean Pelvic Floor Distress Inventory (PFDI) scores of women with and without fibromyalgia. Results: The prevalence of fibromyalgia in women evaluated for initial urogynecology consultation during the study period was 114 out of 1,113 (7%). Women with fibromyalgia reported significantly higher symptom bother scores related to pelvic organ prolapse, defecatory dysfunction, urinary symptoms, and sexual function: PFDI (p=0.005), PFIQ (p=0.010), and PISQ (p=0.018). Women with fibromyalgia were found to have a higher BMI (p=0.008) and were more likely to report a history of sexual abuse, OR 3.1 (95% CI 1.3, 7.9), and have levator myalgia on examination, OR 3.8 (95% CI 1.5, 9.1). In a linear regression analysis, levator myalgia was found to be the significant factor associated with pelvic floor symptom bother. Conclusions: In women with symptomatic prolapse, fibromyalgia is associated with an increased risk of levator myalgia and 50% more symptom bother from pelvic floor disorders.

Original languageEnglish (US)
Pages (from-to)677-682
Number of pages6
JournalInternational Urogynecology Journal and Pelvic Floor Dysfunction
Issue number5
StatePublished - May 2014


  • Central sensitization
  • Fibromyalgia
  • Levator myalgia
  • Pelvic floor
  • Prolapse
  • Symptombother

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Urology

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