Does 2-Hydroxyestrone suppress prolactin in women?

George R. Merriam, Shinzo Kono, D. Lynn Loriaux, Mortimer B. Lipsett

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The catechol estrogen 2-hydroxyestrone was administered iv to six normal women at a dose of 80 μg/h for 4 h. In contrast to previous studies, no suppression of plasma PRL concentrations and no effect on LH or FSH were observed. We found no evidence to suggest that this compound behaves peripherally as anything other than a weak estrogen.

Original languageEnglish (US)
Pages (from-to)753-756
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Issue number4
StatePublished - Apr 1982
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical


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