DNA microarray and proteomic strategies for understanding alcohol action

James M. Sikela, Erik J. MacLaren, Young Kim, Anis Karimpour-Fard, Wei Wen Cai, Jonathan Pollack, Robert Hitzemann, John Belknap, Shannon McWeeney, Robnet T. Kerns, Chris Downing, Thomas E. Johnson, Kathleen J. Grant, Boris Tabakoff, Paula Hoffman, Christine C. Wu, Michael F. Miles

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

This article summarizes the proceedings of a symposium presented at the 2005 annual meeting of the Research Society on Alcoholism in Santa Barbara, California. The organizer was James M. Sikela, and he and Michael F. Miles were chairs. The presentations were (1) Genomewide Surveys of Gene Copy Number Variation in Human and Mouse: Implications for the Genetics of Alcohol Action, by James M. Sikela; (2) Regional Differences in the Regulation of Brain Gene Expression: Relevance to the Detection of Genes Associated with Alcohol-Related Traits, by Robert Hitzemann; (3) Identification of Ethanol Quantitative Trait Loci Candidate Genes by Expression Profiling in Inbred Long Sleep/Inbred Short Sleep Congenic Mice, by Robnet T. Kerns; and (4) Quantitative Proteomic Analysis of AC7-Modified Mice, by Kathleen J. Grant.

Original languageEnglish (US)
Pages (from-to)700-708
Number of pages9
JournalAlcoholism: Clinical and Experimental Research
Volume30
Issue number4
DOIs
StatePublished - Apr 2006
Externally publishedYes

Keywords

  • Adenylyl Cyclase
  • Alcohol-Related QTL
  • Array-Based Comparative Genomic Hybridization
  • Gene Copy Number
  • Gene Expression Profiling
  • Microarrays
  • Proteomics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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