TY - JOUR
T1 - Distribution of Substance P Neurons in the Epithalamus of the Rat
T2 - An Immunohistochemical Investigation
AU - Rønnekleiv, Oline K.
AU - Kelly, Martin J.
PY - 1984/10
Y1 - 1984/10
N2 - Substance P (SP) immunoreactivity was studied in the epithalamus of intact and superior cervical ganglionectomized female rats by using the peroxidase‐antiperoxidase immunocytochemical technique. Cells containing immunoreactive SP were located in the medial habenula, and SP fibers were observed in the lateral habenula, habenular commissure, pineal stalk, and the pineal organ. Bilateral removal of the superior cervical ganglia did not affect the immunocytochemical staining of SP‐containing cells and fibers 15–30 days later. It is suggested that habenular neurons containing SP send projections into the pineal organ of the rat.
AB - Substance P (SP) immunoreactivity was studied in the epithalamus of intact and superior cervical ganglionectomized female rats by using the peroxidase‐antiperoxidase immunocytochemical technique. Cells containing immunoreactive SP were located in the medial habenula, and SP fibers were observed in the lateral habenula, habenular commissure, pineal stalk, and the pineal organ. Bilateral removal of the superior cervical ganglia did not affect the immunocytochemical staining of SP‐containing cells and fibers 15–30 days later. It is suggested that habenular neurons containing SP send projections into the pineal organ of the rat.
KW - habenula
KW - pineal organ
KW - substance P
KW - superior cervical ganglionectomy
UR - http://www.scopus.com/inward/record.url?scp=0021719690&partnerID=8YFLogxK
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U2 - 10.1111/j.1600-079X.1984.tb00226.x
DO - 10.1111/j.1600-079X.1984.tb00226.x
M3 - Article
C2 - 6085878
AN - SCOPUS:0021719690
SN - 0742-3098
VL - 1
SP - 355
EP - 370
JO - Journal of pineal research
JF - Journal of pineal research
IS - 4
ER -