Distribution of D5 dopamine receptor mRNA in rat brain

James H. Meador-Woodruff, Alfred Mansour, David Grandy, Scott P. Damask, Olivier Civelli, Stanley J. Watson

    Research output: Contribution to journalArticle

    131 Citations (Scopus)

    Abstract

    The distribution of the messenger RNA encoding the dopamine D5 receptor was determined in the rat brain by in situ hybridization. Using [35S]-labelled riboprobes to either the rat or human D5 receptor, this mRNA was localized to the hippocampus and the parafascicular nucleus of the thalamus. This mRNA could not be visualized in the more traditional brain regions associated with dopaminergic cell bodies or projection fields. This unusual distribution suggests a novel function in the brain for this subtype of the dopamine receptor.

    Original languageEnglish (US)
    Pages (from-to)209-212
    Number of pages4
    JournalNeuroscience Letters
    Volume145
    Issue number2
    DOIs
    StatePublished - Oct 12 1992

    Fingerprint

    Dopamine D5 Receptors
    Messenger RNA
    Brain
    Intralaminar Thalamic Nuclei
    Dopamine Receptors
    In Situ Hybridization
    Hippocampus

    Keywords

    • Catecholamine
    • Dopamine
    • Messenger
    • Receptor
    • RNA

    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this

    Meador-Woodruff, J. H., Mansour, A., Grandy, D., Damask, S. P., Civelli, O., & Watson, S. J. (1992). Distribution of D5 dopamine receptor mRNA in rat brain. Neuroscience Letters, 145(2), 209-212. https://doi.org/10.1016/0304-3940(92)90024-2

    Distribution of D5 dopamine receptor mRNA in rat brain. / Meador-Woodruff, James H.; Mansour, Alfred; Grandy, David; Damask, Scott P.; Civelli, Olivier; Watson, Stanley J.

    In: Neuroscience Letters, Vol. 145, No. 2, 12.10.1992, p. 209-212.

    Research output: Contribution to journalArticle

    Meador-Woodruff, JH, Mansour, A, Grandy, D, Damask, SP, Civelli, O & Watson, SJ 1992, 'Distribution of D5 dopamine receptor mRNA in rat brain', Neuroscience Letters, vol. 145, no. 2, pp. 209-212. https://doi.org/10.1016/0304-3940(92)90024-2
    Meador-Woodruff JH, Mansour A, Grandy D, Damask SP, Civelli O, Watson SJ. Distribution of D5 dopamine receptor mRNA in rat brain. Neuroscience Letters. 1992 Oct 12;145(2):209-212. https://doi.org/10.1016/0304-3940(92)90024-2
    Meador-Woodruff, James H. ; Mansour, Alfred ; Grandy, David ; Damask, Scott P. ; Civelli, Olivier ; Watson, Stanley J. / Distribution of D5 dopamine receptor mRNA in rat brain. In: Neuroscience Letters. 1992 ; Vol. 145, No. 2. pp. 209-212.
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