Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study

Rachel H. MacKey, Steven H. Belle, Anita P. Courcoulas, Greg F. Dakin, Clifford Deveney, David R. Flum, Luis Garcia, Wendy C. King, Lewis H. Kuller, James E. Mitchell, Alfons Pomp, Walter J. Pories, Bruce Wolfe

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Primary prevention guidelines recommend calculation of lifetime cardiovascular disease (CVD) predicted risk in patients who may not meet criteria for high short-term (10-year) Adult Treatment Panel III risk for coronary heart disease (CHD). Extreme obesity and bariatric surgery are more common in women who often have low short-term predicted CHD risk. The distribution and correlates of lifetime CVD predicted risk, however, have not yet been evaluated in bariatric surgical candidates. Using established 10-year (Adult Treatment Panel III) CHD and lifetime CVD risk prediction algorithms and presurgery risk factors, participants from the Longitudinal Assessment of Bariatric Surgery-2 study without prevalent CVD (n = 2,070) were stratified into 3 groups: low 10-year (2. High 10-year CHD predicted risk was common (36.5%) and associated with diabetes, male gender, and older age, but not with higher body mass index or high-sensitivity C-reactive protein. Most participants (76%) with low 10-year predicted risk had high lifetime CVD predicted risk, which was associated with dyslipidemia and hypertension but not with body mass index, waist circumference, high-density lipoprotein cholesterol, or high-sensitivity C-reactive protein. In conclusion, bariatric surgical candidates without diabetes or existing CVD are likely to have low short-term, but high lifetime CVD predicted risk. Current data support the need for long-term monitoring and treatment of increased CVD risk factors in bariatric surgical patients to maximize lifetime CVD risk decrease.

Original languageEnglish (US)
Pages (from-to)1130-1137
Number of pages8
JournalAmerican Journal of Cardiology
Volume110
Issue number8
DOIs
StatePublished - Oct 15 2012

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Bariatric Surgery
Cardiovascular Diseases
Bariatrics
Coronary Disease
C-Reactive Protein
Body Mass Index
Waist Circumference
Primary Prevention
Dyslipidemias
HDL Cholesterol
Therapeutics
Obesity
Guidelines
Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study. / MacKey, Rachel H.; Belle, Steven H.; Courcoulas, Anita P.; Dakin, Greg F.; Deveney, Clifford; Flum, David R.; Garcia, Luis; King, Wendy C.; Kuller, Lewis H.; Mitchell, James E.; Pomp, Alfons; Pories, Walter J.; Wolfe, Bruce.

In: American Journal of Cardiology, Vol. 110, No. 8, 15.10.2012, p. 1130-1137.

Research output: Contribution to journalArticle

MacKey, RH, Belle, SH, Courcoulas, AP, Dakin, GF, Deveney, C, Flum, DR, Garcia, L, King, WC, Kuller, LH, Mitchell, JE, Pomp, A, Pories, WJ & Wolfe, B 2012, 'Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study', American Journal of Cardiology, vol. 110, no. 8, pp. 1130-1137. https://doi.org/10.1016/j.amjcard.2012.05.054
MacKey, Rachel H. ; Belle, Steven H. ; Courcoulas, Anita P. ; Dakin, Greg F. ; Deveney, Clifford ; Flum, David R. ; Garcia, Luis ; King, Wendy C. ; Kuller, Lewis H. ; Mitchell, James E. ; Pomp, Alfons ; Pories, Walter J. ; Wolfe, Bruce. / Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study. In: American Journal of Cardiology. 2012 ; Vol. 110, No. 8. pp. 1130-1137.
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AU - Deveney, Clifford

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AU - Garcia, Luis

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