TY - JOUR
T1 - Distal convoluted tubule
AU - Subramanya, Arohan R.
AU - Ellison, David H.
N1 - Publisher Copyright:
Copyright © 2014 by the American Society of Nephrology.
PY - 2014
Y1 - 2014
N2 - The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule regulates these processes at the molecular level. This article provides an update on the distal convoluted tubule, highlighting concepts and pathophysiology relevant to clinical practice.
AB - The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule regulates these processes at the molecular level. This article provides an update on the distal convoluted tubule, highlighting concepts and pathophysiology relevant to clinical practice.
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U2 - 10.2215/CJN.05920613
DO - 10.2215/CJN.05920613
M3 - Article
C2 - 24855283
AN - SCOPUS:84920574327
SN - 1555-9041
VL - 9
SP - 2147
EP - 2163
JO - Clinical Journal of the American Society of Nephrology
JF - Clinical Journal of the American Society of Nephrology
IS - 12
ER -