Distal convoluted tubule

Arohan R. Subramanya, David Ellison

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule regulates these processes at the molecular level. This article provides an update on the distal convoluted tubule, highlighting concepts and pathophysiology relevant to clinical practice.

Original languageEnglish (US)
Pages (from-to)2147-2163
Number of pages17
JournalClinical Journal of the American Society of Nephrology
Volume9
Issue number12
DOIs
StatePublished - 2014

Fingerprint

Nephrons
Divalent Cations
Potassium
Homeostasis
Sodium

ASJC Scopus subject areas

  • Nephrology
  • Transplantation
  • Epidemiology
  • Critical Care and Intensive Care Medicine

Cite this

Distal convoluted tubule. / Subramanya, Arohan R.; Ellison, David.

In: Clinical Journal of the American Society of Nephrology, Vol. 9, No. 12, 2014, p. 2147-2163.

Research output: Contribution to journalArticle

Subramanya, Arohan R. ; Ellison, David. / Distal convoluted tubule. In: Clinical Journal of the American Society of Nephrology. 2014 ; Vol. 9, No. 12. pp. 2147-2163.
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