Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

Daniel M. Gibbs

Research output: Contribution to journalArticle

214 Scopus citations


Oxytocin (OT), vasopressin (AVP), and corticotropin (ACTH) levels were measured in peripheral plasma of male rats subjected to one of three models of stress: restraint, cold, or ether. ACTH secretion was increased in all three groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether but not cold. AVP secretion was increased only by ether stress. The data suggest that the hypothalamic and neurohypophysial contribution to the control of ACTH secretion may vary in response to different types of stress.

Original languageEnglish (US)
Pages (from-to)487-491
Number of pages5
JournalLife Sciences
Issue number5
StatePublished - Jul 30 1984


ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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