Abstract
Purpose: To examine the link between symptoms of hyperactivity-inattention and conduct disorder in childhood, and the initiation of tobacco and cannabis use, controlling for other behavioral symptoms, temperament and environmental risk factors. Method: The sample (N=1107 participants, aged 4 to 18 years at baseline) was recruited from the population-based longitudinal Gazel Youth study with a follow-up assessment 8 years later. Psychopathology, temperament, environmental variables, and initiation of tobacco and cannabis use were self-reported. Event time analyses were performed to assess the effects of childhood disruptive symptoms on age at first use of tobacco and cannabis. Results: Proportional hazard models revealed that participants with high levels of childhood symptoms of both hyperactivity-inattention and conduct disorder were at highest risk of early tobacco initiation (in males: hazard ratio [HR]. =2.05; confidence interval [CI]: 1.24-3.38; in females: HR. =2.01; CI: 1.31-3.09), and, in males, of early cannabis initiation (HR. =1.95; CI: 1.04-3.64). Temperament, through activity in both males and females and negative emotionality in females, was also associated to early substance use initiation. Conclusions: Children who simultaneously have high levels of symptoms of hyperactivity-inattention and conduct disorder are at increased risk for early substance initiation. These associations may guide childhood health professionals to consider the liability for early substance initiation in high-risk groups.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 402-408 |
| Number of pages | 7 |
| Journal | European Psychiatry |
| Volume | 25 |
| Issue number | 7 |
| DOIs | |
| State | Published - Nov 2010 |
| Externally published | Yes |
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Keywords
- Attention deficit hyperactivity disorder
- Conduct disorder
- Epidemiology
- Externalizing behavior disorders
- Marijuana
- Tobacco
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Disruptive symptoms in childhood and adolescence and early initiation of tobacco and cannabis use : The Gazel Youth study. / Galéra, C.; Bouvard, M. P.; Melchior, M.; Chastang, J. F.; Lagarde, E.; Michel, G.; Encrenaz, G.; Messiah, A.; Fombonne, Eric.
In: European Psychiatry, Vol. 25, No. 7, 11.2010, p. 402-408.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Disruptive symptoms in childhood and adolescence and early initiation of tobacco and cannabis use
T2 - The Gazel Youth study
AU - Galéra, C.
AU - Bouvard, M. P.
AU - Melchior, M.
AU - Chastang, J. F.
AU - Lagarde, E.
AU - Michel, G.
AU - Encrenaz, G.
AU - Messiah, A.
AU - Fombonne, Eric
PY - 2010/11
Y1 - 2010/11
N2 - Purpose: To examine the link between symptoms of hyperactivity-inattention and conduct disorder in childhood, and the initiation of tobacco and cannabis use, controlling for other behavioral symptoms, temperament and environmental risk factors. Method: The sample (N=1107 participants, aged 4 to 18 years at baseline) was recruited from the population-based longitudinal Gazel Youth study with a follow-up assessment 8 years later. Psychopathology, temperament, environmental variables, and initiation of tobacco and cannabis use were self-reported. Event time analyses were performed to assess the effects of childhood disruptive symptoms on age at first use of tobacco and cannabis. Results: Proportional hazard models revealed that participants with high levels of childhood symptoms of both hyperactivity-inattention and conduct disorder were at highest risk of early tobacco initiation (in males: hazard ratio [HR]. =2.05; confidence interval [CI]: 1.24-3.38; in females: HR. =2.01; CI: 1.31-3.09), and, in males, of early cannabis initiation (HR. =1.95; CI: 1.04-3.64). Temperament, through activity in both males and females and negative emotionality in females, was also associated to early substance use initiation. Conclusions: Children who simultaneously have high levels of symptoms of hyperactivity-inattention and conduct disorder are at increased risk for early substance initiation. These associations may guide childhood health professionals to consider the liability for early substance initiation in high-risk groups.
AB - Purpose: To examine the link between symptoms of hyperactivity-inattention and conduct disorder in childhood, and the initiation of tobacco and cannabis use, controlling for other behavioral symptoms, temperament and environmental risk factors. Method: The sample (N=1107 participants, aged 4 to 18 years at baseline) was recruited from the population-based longitudinal Gazel Youth study with a follow-up assessment 8 years later. Psychopathology, temperament, environmental variables, and initiation of tobacco and cannabis use were self-reported. Event time analyses were performed to assess the effects of childhood disruptive symptoms on age at first use of tobacco and cannabis. Results: Proportional hazard models revealed that participants with high levels of childhood symptoms of both hyperactivity-inattention and conduct disorder were at highest risk of early tobacco initiation (in males: hazard ratio [HR]. =2.05; confidence interval [CI]: 1.24-3.38; in females: HR. =2.01; CI: 1.31-3.09), and, in males, of early cannabis initiation (HR. =1.95; CI: 1.04-3.64). Temperament, through activity in both males and females and negative emotionality in females, was also associated to early substance use initiation. Conclusions: Children who simultaneously have high levels of symptoms of hyperactivity-inattention and conduct disorder are at increased risk for early substance initiation. These associations may guide childhood health professionals to consider the liability for early substance initiation in high-risk groups.
KW - Attention deficit hyperactivity disorder
KW - Conduct disorder
KW - Epidemiology
KW - Externalizing behavior disorders
KW - Marijuana
KW - Tobacco
UR - http://www.scopus.com/inward/record.url?scp=77958494714&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77958494714&partnerID=8YFLogxK
U2 - 10.1016/j.eurpsy.2010.06.002
DO - 10.1016/j.eurpsy.2010.06.002
M3 - Article
C2 - 20813507
AN - SCOPUS:77958494714
VL - 25
SP - 402
EP - 408
JO - European Psychiatry
JF - European Psychiatry
SN - 0924-9338
IS - 7
ER -