Disruptive symptoms in childhood and adolescence and early initiation of tobacco and cannabis use: The Gazel Youth study

C. Galéra, M. P. Bouvard, M. Melchior, J. F. Chastang, E. Lagarde, G. Michel, G. Encrenaz, A. Messiah, E. Fombonne

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Purpose: To examine the link between symptoms of hyperactivity-inattention and conduct disorder in childhood, and the initiation of tobacco and cannabis use, controlling for other behavioral symptoms, temperament and environmental risk factors. Method: The sample (N=1107 participants, aged 4 to 18 years at baseline) was recruited from the population-based longitudinal Gazel Youth study with a follow-up assessment 8 years later. Psychopathology, temperament, environmental variables, and initiation of tobacco and cannabis use were self-reported. Event time analyses were performed to assess the effects of childhood disruptive symptoms on age at first use of tobacco and cannabis. Results: Proportional hazard models revealed that participants with high levels of childhood symptoms of both hyperactivity-inattention and conduct disorder were at highest risk of early tobacco initiation (in males: hazard ratio [HR]. =2.05; confidence interval [CI]: 1.24-3.38; in females: HR. =2.01; CI: 1.31-3.09), and, in males, of early cannabis initiation (HR. =1.95; CI: 1.04-3.64). Temperament, through activity in both males and females and negative emotionality in females, was also associated to early substance use initiation. Conclusions: Children who simultaneously have high levels of symptoms of hyperactivity-inattention and conduct disorder are at increased risk for early substance initiation. These associations may guide childhood health professionals to consider the liability for early substance initiation in high-risk groups.

Original languageEnglish (US)
Pages (from-to)402-408
Number of pages7
JournalEuropean Psychiatry
Volume25
Issue number7
DOIs
StatePublished - Nov 2010

Keywords

  • Attention deficit hyperactivity disorder
  • Conduct disorder
  • Epidemiology
  • Externalizing behavior disorders
  • Marijuana
  • Tobacco

ASJC Scopus subject areas

  • Psychiatry and Mental health

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