Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Pre-eclampsia in Asymptomatic Women

The PAPR Study Consortium

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4 Scopus citations

Abstract

Srinivasan et al. use maternal serum to identify and verify miRNA biomarkers in asymptomatic patients at elevated risk for later development of pre-eclampsia in independent cohorts. Biostatistical analyses show that the verification rate for the reversals using bivariate models is markedly higher than for univariate biomarkers.

Original languageEnglish (US)
Article number100013
JournalCell Reports Medicine
Volume1
Issue number2
DOIs
StatePublished - May 19 2020

Keywords

  • biomarkers
  • bivariate
  • extracellular RNA
  • extracellular vesicle
  • maternal serum
  • miR-155-5p
  • miRNA
  • placenta
  • pre-eclampsia
  • small RNA-seq

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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