Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C

Marilyn Huckans, Adriana Seelye, Jonathan Woodhouse, Tiffany Parcel, Lisa Mull, Daniel Schwartz, Alex Mitchell, David Lahna, Amy Johnson, Jennifer Loftis, Steven Paul Woods, Suzanne H. Mitchell, William Hoffman

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Objective: Determine whether adults with hepatitis C (HCV), regardless of substance use disorder, are more likely to discount delayed rewards than adults without hepatitis C, and explore the relationship between delay discounting and neuropsychological functioning. Methods: Procedures included clinical interviews, neuropsychological testing, and a delay discounting task. Results: Regardless of substance abuse history, adults with hepatitis C were significantly more likely to choose smaller immediate rewards over larger delayed rewards. Delay discounting correlated with performance on executive functioning tasks. Conclusions: Increased discounting is associated with broad executive dysfunction, suggesting that HCV-associated executive dysfunction may lead to altered decision-making style.

Original languageEnglish (US)
Pages (from-to)176-186
Number of pages11
JournalJournal of Clinical and Experimental Neuropsychology
Volume33
Issue number2
DOIs
StatePublished - Feb 2011

Keywords

  • Delay discounting
  • Hepatitis C
  • Impulsive behavior
  • Neuropsychology
  • Substance-related disorders

ASJC Scopus subject areas

  • Clinical Psychology
  • Neurology
  • Clinical Neurology

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