Disability index in a randomized controlled trial of emergency sclerotherapy versus portacaval shunt for bleeding varices in cirrhosis

Marshall J. Orloff, Jon I. Isenberg, Henry O. Wheeler, Kevin S. Haynes, Horacio Jinich-Brook, Roderick Rapier, Florin Vaida, Robert J. Hye, Susan Orloff

Research output: Contribution to journalArticle

Abstract

Background: Disability has not been studied after emergency treatment of bleeding esophageal varices (BEV). We created a disability index (DI) in a randomized controlled trial comparing emergency endoscopic therapy (EST) versus emergency portacaval shunt (EPCS). Methods: There were 211 unselected, consecutive patients with cirrhosis and acute BEV who were randomized to EST (n = 106) or EPCS (n = 105). Diagnostic work-up and treatment were performed within 8 hours. Ninety-six percent underwent more than 10 years follow-up evaluation. Disability was measured by assessing 9 factors to create a DI. Results: Ten-year survival was 8% after EST versus 51% after EPCS (P

Original languageEnglish (US)
Pages (from-to)157-166
Number of pages10
JournalAmerican Journal of Surgery
Volume204
Issue number2
DOIs
StatePublished - Aug 2012

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Surgical Portacaval Shunt
Sclerotherapy
Varicose Veins
Emergencies
Fibrosis
Emergency Treatment
Esophageal and Gastric Varices
Randomized Controlled Trials
Hemorrhage
Therapeutics
Survival

Keywords

  • Bleeding varices
  • Endoscopic sclerotherapy
  • Portacaval shunt
  • Quality of life

ASJC Scopus subject areas

  • Surgery

Cite this

Disability index in a randomized controlled trial of emergency sclerotherapy versus portacaval shunt for bleeding varices in cirrhosis. / Orloff, Marshall J.; Isenberg, Jon I.; Wheeler, Henry O.; Haynes, Kevin S.; Jinich-Brook, Horacio; Rapier, Roderick; Vaida, Florin; Hye, Robert J.; Orloff, Susan.

In: American Journal of Surgery, Vol. 204, No. 2, 08.2012, p. 157-166.

Research output: Contribution to journalArticle

Orloff, Marshall J. ; Isenberg, Jon I. ; Wheeler, Henry O. ; Haynes, Kevin S. ; Jinich-Brook, Horacio ; Rapier, Roderick ; Vaida, Florin ; Hye, Robert J. ; Orloff, Susan. / Disability index in a randomized controlled trial of emergency sclerotherapy versus portacaval shunt for bleeding varices in cirrhosis. In: American Journal of Surgery. 2012 ; Vol. 204, No. 2. pp. 157-166.
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AU - Jinich-Brook, Horacio

AU - Rapier, Roderick

AU - Vaida, Florin

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