Direction selectivity in the retina: Symmetry and asymmetry in structure and function

David I. Vaney; Benjamin Sivyer; W. Rowland Taylor

doi:10.1038/nrn3165

Direction selectivity in the retina: Symmetry and asymmetry in structure and function

David I. Vaney, Benjamin Sivyer, W. Rowland Taylor

Research output: Contribution to journal › Review article › peer-review

207 Scopus citations

Abstract

Visual information is processed in the retina to a remarkable degree before it is transmitted to higher visual centres. Several types of retinal ganglion cells (the output neurons of the retina) respond preferentially to image motion in a particular direction, and each type of direction-selective ganglion cell (DSGC) is comprised of multiple subtypes with different preferred directions. The direction selectivity of the cells is generated by diverse mechanisms operating within microcircuits that rely on independent neuronal processing in individual dendrites of both the DSGCs and the presynaptic neurons that innervate them.

Original language	English (US)
Pages (from-to)	194-208
Number of pages	15
Journal	Nature Reviews Neuroscience
Volume	13
Issue number	3
DOIs	https://doi.org/10.1038/nrn3165
State	Published - Mar 2012
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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title = "Direction selectivity in the retina: Symmetry and asymmetry in structure and function",

abstract = "Visual information is processed in the retina to a remarkable degree before it is transmitted to higher visual centres. Several types of retinal ganglion cells (the output neurons of the retina) respond preferentially to image motion in a particular direction, and each type of direction-selective ganglion cell (DSGC) is comprised of multiple subtypes with different preferred directions. The direction selectivity of the cells is generated by diverse mechanisms operating within microcircuits that rely on independent neuronal processing in individual dendrites of both the DSGCs and the presynaptic neurons that innervate them.",

author = "Vaney, {David I.} and Benjamin Sivyer and Taylor, {W. Rowland}",

note = "Funding Information: This paper is dedicated to Horace Barlow on the occasion of his ninetieth birthday and Bill Levick on the occasion of his eightieth birthday, in recognition of their outstanding pioneering studies on direction selectivity in the retina, which laid the foundation for the research described in this Review. W.R.T. is supported by a grant from the National Eye Institute (EY014888) and a Lew R. Wasserman Award from Research to Prevent Blindness.",

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AB - Visual information is processed in the retina to a remarkable degree before it is transmitted to higher visual centres. Several types of retinal ganglion cells (the output neurons of the retina) respond preferentially to image motion in a particular direction, and each type of direction-selective ganglion cell (DSGC) is comprised of multiple subtypes with different preferred directions. The direction selectivity of the cells is generated by diverse mechanisms operating within microcircuits that rely on independent neuronal processing in individual dendrites of both the DSGCs and the presynaptic neurons that innervate them.

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Direction selectivity in the retina: Symmetry and asymmetry in structure and function

Abstract

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